Kasuya J, Hashimoto Y, Terasaki T, Shimamura M, Uchino M
Department of Strokology, Kumamoto City Hospital.
Rinsho Shinkeigaku. 2000 Jul;40(7):707-11.
We presented a patient of cerebral embolism caused by Libman-Sacks endocarditis with systemic lupus erythematosus (SLE). This 35-year-old housewife with SLE suffered from abrupt visual disturbance in December 1998. Angiography revealed the occlusion of her right posterior cerebral artery. Transesophageal echocardiography showed the mitral regurgitation and hyperplasia of the anterior mitral valve leaflet without vegetation. In April 1999, she again suffered from sudden onset of transient left hemiparesis and dysphasia. Angiographic findings were unchanged. Transesophageal echocardiographic examination detected vegetation on the anterior mitral valve leaflet and aggravation of the mitral regurgitation. Laboratory examination revealed inactivity of SLE. No bacteria was recovered from repeated blood cultures. We diagnosed that Libman-Sacks vegetation caused cerebral embolism.
我们报告了一例由利布曼-萨克斯心内膜炎导致脑栓塞的系统性红斑狼疮（SLE）患者。这位35岁患有SLE的家庭主妇于1998年12月突然出现视力障碍。血管造影显示其右侧大脑后动脉闭塞。经食管超声心动图显示二尖瓣反流以及二尖瓣前叶增生但无赘生物。1999年4月，她再次突然出现短暂性左半身轻瘫和言语困难。血管造影结果未变。经食管超声心动图检查发现二尖瓣前叶有赘生物且二尖瓣反流加重。实验室检查显示SLE处于非活动期。多次血培养均未检出细菌。我们诊断为利布曼-萨克斯赘生物导致脑栓塞。
