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紧急与早期开始腹膜透析:患者特征和结局。

Urgent vs. early-start peritoneal dialysis: patients' profile and outcomes.

机构信息

Fundação Pró-Rim, Joinville, SC, Brasil.

Universidade da Região de Joinville - Univille, Escola de Medicina, Joinville, SC, Brasil.

出版信息

J Bras Nefrol. 2021 Jan-Mar;43(1):110-114. doi: 10.1590/2175-8239-JBN-2020-0011.

Abstract

INTRODUCTION

Peritoneal dialysis (PD) has been considered a safe option of therapy in end-stage renal disease patients with urgent need of dialysis. Recently, it was proposed that Urgent-Start-PD (US-PD) be defined when PD starts within 72 hours after catheter placement and "early start" PD (ES-PD) when PD starts between 3 and 14 days after. We aimed to compare demographic and clinical characteristics between patients in US-PD and ES-PD as well as 30-day complications, 6-month hospitalization, and dropout rate.

METHODS

Adult patients starting PD within 14 days after catheter insertion (October/2016 - February/2019) were included and divided into US-PD group and ES-PD group based on the their PD initiation time. Clinical and demographic data, fill volume for the first PD session, 30-day complications, 6-month hospitalization, and dropout rate were assessed.

RESULTS

In our study, 72 patients were analyzed (US-PD=40, ES-PD=32) with mean age of 53.2±15.2 years old. No differences between US-PD and ES-PD regarding demographic characteristics, 30-day complications, 6-month hospitalization, and dropout events were found. The most frequent short-term complication in patients who started PD urgently was leakage. The most common cause of dropout was transfer to HD.

CONCLUSION

Fifty five percent of our sample started PD less than 72 hours after catheter insertion. The lack of difference in the measured outcomes compared to patients that had therapy initiated after this period encourages the use of urgent PD when needed.

摘要

简介

腹膜透析(PD)已被认为是终末期肾病患者紧急透析的安全治疗选择。最近,有人提出,PD 在导管放置后 72 小时内开始时应定义为紧急开始 PD(US-PD),而 PD 在 3 至 14 天后开始时应定义为早期开始 PD(ES-PD)。我们旨在比较 US-PD 和 ES-PD 患者的人口统计学和临床特征,以及 30 天并发症、6 个月住院和退出率。

方法

纳入在导管插入后 14 天内开始 PD 的成年患者(2016 年 10 月至 2019 年 2 月),并根据 PD 开始时间将其分为 US-PD 组和 ES-PD 组。评估临床和人口统计学数据、第一次 PD 治疗的填充量、30 天并发症、6 个月住院和退出率。

结果

本研究共分析了 72 例患者(US-PD=40,ES-PD=32),平均年龄为 53.2±15.2 岁。US-PD 和 ES-PD 两组在人口统计学特征、30 天并发症、6 个月住院和退出事件方面无差异。紧急开始 PD 的患者最常见的短期并发症是渗漏。退出的最常见原因是转至 HD。

结论

我们的样本中有 55%的患者在导管插入后不到 72 小时就开始进行 PD。与在此期间后开始治疗的患者相比,在测量结果方面没有差异,这鼓励在需要时使用紧急 PD。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/79e9/8061954/5ab03046471e/2175-8239-jbn-2020-0011-gf01.jpg

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