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美国新冠病毒从城市向农村地区的传播:流行率的时空分析。

Progression of COVID-19 From Urban to Rural Areas in the United States: A Spatiotemporal Analysis of Prevalence Rates.

机构信息

Department of Public Health Sciences, University of North Carolina at Charlotte, Charlotte, North Carolina.

Department of Mathematics, University of Louisville, Louisville, Kentucky.

出版信息

J Rural Health. 2020 Sep;36(4):591-601. doi: 10.1111/jrh.12486. Epub 2020 Jun 30.

Abstract

PURPOSE

There are growing signs that the COVID-19 virus has started to spread to rural areas and can impact the rural health care system that is already stretched and lacks resources. To aid in the legislative decision process and proper channelizing of resources, we estimated and compared the county-level change in prevalence rates of COVID-19 by rural-urban status over 3 weeks. Additionally, we identified hotspots based on estimated prevalence rates.

METHODS

We used crowdsourced data on COVID-19 and linked them to county-level demographics, smoking rates, and chronic diseases. We fitted a Bayesian hierarchical spatiotemporal model using the Markov Chain Monte Carlo algorithm in R-studio. We mapped the estimated prevalence rates using ArcGIS 10.8, and identified hotspots using Gettis-Ord local statistics.

FINDINGS

In the rural counties, the mean prevalence of COVID-19 increased from 3.6 per 100,000 population to 43.6 per 100,000 within 3 weeks from April 3 to April 22, 2020. In the urban counties, the median prevalence of COVID-19 increased from 10.1 per 100,000 population to 107.6 per 100,000 within the same period. The COVID-19 adjusted prevalence rates in rural counties were substantially elevated in counties with higher black populations, smoking rates, and obesity rates. Counties with high rates of people aged 25-49 years had increased COVID-19 prevalence rates.

CONCLUSIONS

Our findings show a rapid spread of COVID-19 across urban and rural areas in 21 days. Studies based on quality data are needed to explain further the role of social determinants of health on COVID-19 prevalence.

摘要

目的

有越来越多的迹象表明,新冠病毒已开始向农村地区传播,并可能影响已经捉襟见肘且资源匮乏的农村医疗保健系统。为了帮助立法决策过程和合理调配资源,我们估算并比较了 3 周内城乡新冠病毒流行率的县级变化。此外,我们还根据估计的流行率确定了热点地区。

方法

我们使用了新冠病毒的众包数据,并将其与县级人口统计数据、吸烟率和慢性病联系起来。我们在 R-studio 中使用马尔可夫链蒙特卡罗算法拟合了贝叶斯分层时空模型。我们使用 ArcGIS 10.8 绘制了估计的流行率图,并使用 Gettis-Ord 局部统计量确定了热点地区。

发现

在农村县,新冠病毒的平均流行率从 4 月 3 日至 4 月 22 日的 3 周内从每 10 万人 3.6 例上升至每 10 万人 43.6 例。在城市县,新冠病毒的中位数流行率从每 10 万人 10.1 例上升至同期的每 10 万人 107.6 例。在黑人人口比例较高、吸烟率和肥胖率较高的县,新冠病毒调整后的流行率显著升高。25-49 岁人群比例较高的县新冠病毒流行率也有所上升。

结论

我们的研究结果表明,新冠病毒在 21 天内迅速在城乡地区传播。需要进行基于高质量数据的研究,以进一步解释社会健康决定因素在新冠病毒流行率中的作用。

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