Emerg Infect Dis. 2024 Nov;30(11):2333-2342. doi: 10.3201/eid3011.231582.
Data on COVID-19 cases, deaths, hospitalizations, and vaccinations in Oklahoma, USA, have not been systematically described. The relationship between vaccination and COVID-19-related outcomes over time has not been investigated. We graphically described data collected during February 2020-December 2021 and conducted spatiotemporal modeling of monthly increases in COVID-19 cumulative death and hospitalization rates, adjusting for cumulative case rate, to explore the relationship. A 1 percentage point increase (absolute change) in the cumulative vaccination rate was associated with a 6.3% (95% CI 1.4%-10.9%) relative decrease in death outcome during April-June 2021, and a 1.9% (95% CI 1.1%-2.6%) relative decrease in death outcome and 1.1% (95% CI 0.5%-1.7%) relative decrease in hospitalization outcome during July-December 2021; the effect on hospitalizations was driven largely by data from urban counties. Our findings from Oklahoma suggest that increasing cumulative vaccination rates might reduce the increase in cumulative death and hospitalization rates from COVID-19.
美国俄克拉荷马州的 COVID-19 病例、死亡、住院和疫苗接种数据尚未系统描述。疫苗接种与 COVID-19 相关结果之间的时间关系尚未得到调查。我们对 2020 年 2 月至 2021 年 12 月期间收集的数据进行了图形描述，并对 COVID-19 累计死亡和住院率的每月增加进行了时空建模，调整了累计病例率，以探讨这种关系。在 2021 年 4 月至 6 月期间，累计疫苗接种率每增加 1 个百分点（绝对变化），与死亡结果相对减少 6.3%（95%CI 1.4%-10.9%）相关，与死亡结果相对减少 1.9%（95%CI 1.1%-2.6%）和住院结果相对减少 1.1%（95%CI 0.5%-1.7%）相关；住院结果的影响主要来自城市县的数据。我们在俄克拉荷马州的发现表明，增加累计疫苗接种率可能会降低 COVID-19 累计死亡和住院率的增加。
