Colman S, Cattoir L, Van Vaerenbergh K, De Beenhouwer H, Boel A
Clinical Laboratory of Microbiology, OLVZ Aalst, Aalst, Belgium.
Acta Gastroenterol Belg. 2020 Apr-Jun;83(2):334-336.
Entamoeba histolytica infections are rare in developed countries such as Belgium. A 53-year-old female patient presented with 10 days of fever and mild persisting pain in the right hypochondriac despite 6 days of antibiotic therapy. The anamnesis further revealed that the patient was born in Colombia and visits her native country on a regular basis. An abdominal CT-scan demonstrated a large hepatic abscess of 10×8 cm. The diagnosis of Entamoeba histolytica- infection was confirmed with real-time PCR (RT-PCR) from the aspirated material of the abscess. Remarkably, a half year ago, this patient also presented to the gastro-enterology consultation with intermittent rectal bleeding, loose stools and abdominal discomfort. Rectosigmoidoscopy at that time showed sigmoiddiverticulosis and biopsies were taken. RT-PCR on this material was performed during this second episode and was positive for E. histolytica, confirming an episode of amoebic colitis a half year prior to the discovery of the liver abscess.
在比利时等发达国家，溶组织内阿米巴感染较为罕见。一名53岁女性患者，尽管接受了6天的抗生素治疗，但仍持续发热10天，右季肋部有轻度持续性疼痛。病史进一步显示，该患者出生于哥伦比亚，且定期前往其祖国。腹部CT扫描显示一个10×8厘米的巨大肝脓肿。通过对脓肿抽吸物进行实时PCR（RT-PCR），确诊为溶组织内阿米巴感染。值得注意的是，半年前，该患者也曾因间歇性直肠出血、腹泻和腹部不适到胃肠病科就诊。当时的直肠乙状结肠镜检查显示乙状结肠憩室病，并进行了活检。在第二次发作期间，对该材料进行了RT-PCR检测，结果显示溶组织内阿米巴呈阳性，证实了在发现肝脓肿半年前曾发生过一次阿米巴结肠炎。
