Suppr超能文献

获得性长 QT 综合征伴急性心肌梗死:一种罕见但潜在致命的实体。

Acquired Long QT Syndrome after Acute Myocardial Infarction: A Rare but Potentially Fatal Entity.

机构信息

Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California 90025.

Division of Cardiology, David Geffen School of Medicine at UCLA, Los Angeles, California 90025.

出版信息

Tex Heart Inst J. 2020 Apr 1;47(2):163-164. doi: 10.14503/THIJ-18-6872.

Abstract

Acquired long QT syndrome is typically caused by medications, electrolyte disturbances, bradycardia, or catastrophic central nervous system events. We report a case of myocardial infarction-related acquired long QT syndrome in a 58-year-old woman that had no clear cause and progressed to torsades de pointes requiring treatment with isoproterenol and magnesium. Despite negative results of DNA testing against a known panel of genetic mutations and polymorphisms associated with long QT syndrome, the patient's family history of fatal cardiac disease suggests a predisposing genetic component. This report serves to remind clinicians of this potentially fatal ventricular arrhythmia after myocardial infarction.

摘要

获得性长 QT 综合征通常由药物、电解质紊乱、心动过缓或灾难性中枢神经系统事件引起。我们报告了一例 58 岁女性与心肌梗死相关的获得性长 QT 综合征,其病因不明确,进展为尖端扭转型室性心动过速,需要异丙肾上腺素和镁治疗。尽管针对与长 QT 综合征相关的已知基因突变和多态性基因检测呈阴性,但该患者家族中存在致命性心脏病病史,提示存在易患遗传因素。本报告旨在提醒临床医生注意心肌梗死后发生这种潜在致命性室性心律失常的可能性。

相似文献

5
Severe Torsades de Pointes with acquired QT prolongation.尖端扭转型室性心动过速伴获得性 QT 间期延长。
Eur Heart J Acute Cardiovasc Care. 2019 Dec;8(8):775-776. doi: 10.1177/2048872616649473. Epub 2016 May 6.
6
Long QT syndrome: first and fatal events provoked by hemodialysis.长QT综合征:血液透析引发的首次致命事件。
Pacing Clin Electrophysiol. 2003 Jan;26(1 Pt 1):103-4. doi: 10.1046/j.1460-9592.2003.00157.x.
8
Long QT syndrome and torsades de pointes complicating mitral valve replacement.长QT综合征与尖端扭转型室速并发二尖瓣置换术。
Indian Heart J. 2016 Sep;68 Suppl 2(Suppl 2):S210-S211. doi: 10.1016/j.ihj.2015.07.015. Epub 2016 Jan 14.

本文引用的文献

1
Acquired long QT syndrome and torsade de pointes.获得性长QT综合征与尖端扭转型室速。
Pacing Clin Electrophysiol. 2018 Apr;41(4):414-421. doi: 10.1111/pace.13296. Epub 2018 Mar 30.
5
QT interval prolongation in acute myocardial infarction.急性心肌梗死中的QT间期延长
Eur Heart J. 1985 Nov;6 Suppl D:85-95. doi: 10.1093/eurheartj/6.suppl_d.85.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验