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Warm Blood Cardioplegia for Myocardial Protection: Concepts and Controversies.温血停搏液在心肌保护中的应用:概念与争议。
Tex Heart Inst J. 2020 Apr 1;47(2):108-116. doi: 10.14503/THIJ-18-6909.
2
The physiologic basis of warm cardioplegia.温血停搏液的生理基础。
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The end of the cold era: from intermittent cold to intermittent warm blood cardioplegia.冷时代的终结:从间歇性冷到间歇性温血心脏停搏液
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The Relationship between the Use of Cold and Isothermic Blood Cardioplegia Solution for Myocardial Protection during Cardiopulmonary Bypass and the Ischemia-Reperfusion Injury.体外循环期间使用冷和等温血停搏液进行心肌保护与缺血-再灌注损伤之间的关系。
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Retrograde cardioplegia does not adequately perfuse the right ventricle.逆行性心脏停搏不能充分灌注右心室。
J Thorac Cardiovasc Surg. 1995 Jun;109(6):1116-24; discussion 1124-6. doi: 10.1016/S0022-5223(95)70195-8.
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Is blood versus crystalloid cardioplegia relevant? Significantly improved protection may require new cardioplegic concepts!血液与晶体停搏液相比重要吗?显著改善的心肌保护可能需要新的心脏停搏概念!
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Intermittent antegrade hyperkalaemic warm blood cardioplegia supplemented with magnesium prevents myocardial substrate derangement in patients undergoing coronary artery bypass surgery.间歇性顺行性高钾温血心脏停搏液补充镁可预防冠状动脉搭桥手术患者的心肌底物紊乱。
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Is warm retrograde blood cardioplegia better than cold for myocardial protection?温血逆行性心脏停搏在心肌保护方面是否优于冷血心脏停搏?
Ann Thorac Surg. 1997 Jan;63(1):98-104. doi: 10.1016/s0003-4975(96)01074-0.

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本文引用的文献

1
Cold crystalloid versus warm blood cardioplegia in patients undergoing aortic valve replacement.接受主动脉瓣置换术患者中冷晶体停搏液与温血心脏停搏液的比较。
J Thorac Dis. 2018 Mar;10(3):1490-1499. doi: 10.21037/jtd.2018.03.67.
2
Six-years survival and predictors of mortality after CABG using cold vs. warm blood cardioplegia in elective and emergent settings.在择期和急诊情况下,使用冷血与温血心脏停搏液进行冠状动脉旁路移植术后的六年生存率及死亡预测因素。
J Cardiothorac Surg. 2015 Dec 4;10:180. doi: 10.1186/s13019-015-0384-9.
3
Endothelial Injury Associated with Cold or Warm Blood Cardioplegia during Coronary Artery Bypass Graft Surgery.冠状动脉搭桥手术中与冷或温血心脏停搏液相关的内皮损伤
Biomed Res Int. 2015;2015:256905. doi: 10.1155/2015/256905. Epub 2015 May 19.
4
Clinical outcomes of intermittent antegrade warm versus cold blood cardioplegia.间歇性顺行温血与冷血心脏停搏液的临床结果
J Pak Med Assoc. 2015 Jun;65(6):593-6.
5
A retrospective analysis of myocardial preservation techniques during coronary artery bypass graft surgery: are we protecting the heart?冠状动脉搭桥手术中心肌保护技术的回顾性分析:我们是否在保护心脏?
J Cardiothorac Surg. 2014 Dec 31;9:184. doi: 10.1186/s13019-014-0184-7.
6
Is there any difference between blood and crystalloid cardioplegia for myocardial protection during cardiac surgery? A meta-analysis of 5576 patients from 36 randomized trials.心脏手术期间,血液停搏液和晶体停搏液在心肌保护方面有差异吗?一项对来自36项随机试验的5576例患者的荟萃分析。
Perfusion. 2012 Nov;27(6):535-46. doi: 10.1177/0267659112453754. Epub 2012 Jul 31.
7
Is cold or warm blood cardioplegia superior for myocardial protection?冷血或温血心脏停搏液在心肌保护方面哪种更具优势?
Interact Cardiovasc Thorac Surg. 2012 Jun;14(6):848-55. doi: 10.1093/icvts/ivs069. Epub 2012 Mar 8.
8
Myocardial protection in cardiac surgery patients requiring prolonged aortic cross-clamp times: a single-center evaluation of clinical outcomes comparing two blood cardioplegic strategies.需要延长主动脉阻断时间的心脏手术患者的心肌保护:比较两种血液停搏液策略的临床结果的单中心评估
J Cardiovasc Surg (Torino). 2010 Dec;51(6):895-905.
9
Warm versus cold cardioplegia for heart surgery: a meta-analysis.温血与冷血心脏停搏液在心脏手术中的应用:一项荟萃分析。
Eur J Cardiothorac Surg. 2010 Apr;37(4):912-9. doi: 10.1016/j.ejcts.2009.09.030. Epub 2009 Oct 21.
10
Myocardial protective effect of warm blood, tepid blood, and cold crystalloid cardioplegia in coronary artery bypass grafting surgery.温血、微温血和冷晶体心脏停搏液在冠状动脉旁路移植手术中的心肌保护作用。
Croat Med J. 2005 Dec;46(6):879-88.

温血停搏液在心肌保护中的应用:概念与争议。

Warm Blood Cardioplegia for Myocardial Protection: Concepts and Controversies.

机构信息

Graduate Medical Education MD/MPH Program, University of Miami Miller School of Medicine, Miami, Florida 33130.

Department of Cardiothoracic Surgery, JFK Medical Center, Atlantis, Florida 33462.

出版信息

Tex Heart Inst J. 2020 Apr 1;47(2):108-116. doi: 10.14503/THIJ-18-6909.

DOI:10.14503/THIJ-18-6909
PMID:32603472
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7328091/
Abstract

Warm blood cardioplegia has been an established cardioplegic method since the 1990s, yet it remains controversial in regard to myocardial protection. This review will describe the physiologic and technical concepts behind warm blood cardioplegia, as well as outline the current basic and clinical research that evaluates its usefulness. Controversies regarding this technique will also be reviewed. A long history of experimental data indicates that warm blood cardioplegia is safe and effective and thus suitable myocardial protection during cardiopulmonary bypass surgeries.

摘要

温血停搏液自 20 世纪 90 年代以来一直是一种成熟的心脏停搏液方法,但在心肌保护方面仍存在争议。本综述将描述温血停搏液背后的生理和技术概念,并概述目前评估其有用性的基础和临床研究。还将回顾关于该技术的争议。大量的实验数据表明,温血停搏液是安全有效的,因此在心肺旁路手术中是合适的心肌保护方法。