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人型支原体滑囊炎在胰腺-肾联合移植受者中的发病:病例报告及文献复习。

Mycoplasma hominis bursitis in a simultaneous pancreas-kidney transplant recipient: case report and literature review.

机构信息

Department of Medicine, Royal Adelaide Hospital, Adelaide, SA, Australia.

Department of Microbiology and Infectious Disease, Flinders Medical Centre, Adelaide, SA, Australia.

出版信息

Transpl Infect Dis. 2020 Dec;22(6):e13392. doi: 10.1111/tid.13392. Epub 2020 Jul 24.

Abstract

Mycoplasma hominis can be isolated frequently from the genitourinary tract of some healthy individuals. On rare occasions, it acts as a pathogen in immunocompromised patients such as transplant recipients. Here, we describe the case of a 39-year-old man with end-stage kidney disease secondary to diabetic nephropathy who received a simultaneous pancreas-kidney transplant. He developed pancreatitis and arterial thrombosis 2 weeks post-transplant and required a pancreatectomy. His kidney allograft function remained normal. He developed severe left hip pain 2 weeks post-transplant with a trochanteric bursal effusion detected on magnetic resonance imaging. The effusion grew M. hominis. The patient was treated with 100 mg of doxycycline twice daily for 9 months with full resolution of the effusion at 4 months post-treatment. We also review all previously reported M. hominis infections in transplant recipients.

摘要

人型支原体可从一些健康个体的泌尿生殖道中频繁分离出来。在极少数情况下,它会在免疫功能低下的患者(如移植受者)中作为病原体发挥作用。在这里,我们描述了一例 39 岁的男性,他患有糖尿病肾病引起的终末期肾病,接受了胰肾联合移植。他在移植后 2 周时发生胰腺炎和动脉血栓形成,需要进行胰切除术。他的肾移植功能保持正常。他在移植后 2 周出现严重的左髋痛,磁共振成像检测到转子滑囊炎积液。该积液中生长出人型支原体。该患者接受了 100mg 多西环素,每日两次,共治疗 9 个月,治疗 4 个月后积液完全消退。我们还回顾了所有先前报道的移植受者中人型支原体感染病例。

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