Department of Medicine, Royal Adelaide Hospital, Adelaide, SA, Australia.
Department of Microbiology and Infectious Disease, Flinders Medical Centre, Adelaide, SA, Australia.
Transpl Infect Dis. 2020 Dec;22(6):e13392. doi: 10.1111/tid.13392. Epub 2020 Jul 24.
Mycoplasma hominis can be isolated frequently from the genitourinary tract of some healthy individuals. On rare occasions, it acts as a pathogen in immunocompromised patients such as transplant recipients. Here, we describe the case of a 39-year-old man with end-stage kidney disease secondary to diabetic nephropathy who received a simultaneous pancreas-kidney transplant. He developed pancreatitis and arterial thrombosis 2 weeks post-transplant and required a pancreatectomy. His kidney allograft function remained normal. He developed severe left hip pain 2 weeks post-transplant with a trochanteric bursal effusion detected on magnetic resonance imaging. The effusion grew M. hominis. The patient was treated with 100 mg of doxycycline twice daily for 9 months with full resolution of the effusion at 4 months post-treatment. We also review all previously reported M. hominis infections in transplant recipients.
人型支原体可从一些健康个体的泌尿生殖道中频繁分离出来。在极少数情况下，它会在免疫功能低下的患者（如移植受者）中作为病原体发挥作用。在这里，我们描述了一例 39 岁的男性，他患有糖尿病肾病引起的终末期肾病，接受了胰肾联合移植。他在移植后 2 周时发生胰腺炎和动脉血栓形成，需要进行胰切除术。他的肾移植功能保持正常。他在移植后 2 周出现严重的左髋痛，磁共振成像检测到转子滑囊炎积液。该积液中生长出人型支原体。该患者接受了 100mg 多西环素，每日两次，共治疗 9 个月，治疗 4 个月后积液完全消退。我们还回顾了所有先前报道的移植受者中人型支原体感染病例。
