家族性进行性前庭蜗神经功能障碍

Familial progressive vestibulocochlear dysfunction.

作者信息

Verhagen W I, Huygen P L, Joosten E M

机构信息

Department of Neurology, Canisius-Wilhelmina Hospital, Nijmegen, the Netherlands.

出版信息

Arch Neurol. 1988 Jul;45(7):766-8. doi: 10.1001/archneur.1988.00520310076020.

DOI:10.1001/archneur.1988.00520310076020

PMID:3260482

Abstract

A kindred is presented in which several members had complaints of head movement-dependent oscillopsia due to acquired vestibular areflexia in combination with progressive hearing loss. History was noncontributory for other neurologic or otologic diseases (including infectious diseases) or use of neuro-ototoxic drugs. The pedigree suggests autosomal dominant inheritance.

摘要

本文报告了一个家族，其中几名成员因获得性前庭反射消失并伴有进行性听力丧失，出现了与头部运动相关的视振荡幻觉的症状。病史中无其他神经或耳科疾病（包括传染病）或使用神经耳毒性药物的情况。家系图谱提示为常染色体显性遗传。