National Organ and Tissue Transplant Organisation, Directorate General of Health Services, Ministry of Health and Family Welfare New Delhi, India; Vardhman Mahavir Medical College and Safdarjung Hospital, New Delhi, India.
Transplant Proc. 2020 Dec;52(10):2930-2933. doi: 10.1016/j.transproceed.2020.04.1824. Epub 2020 Jun 27.
This study addresses the establishment of the National Organ and Tissue Transplant Organisation (NOTTO) and its impact on organ donation and transplantation in India.
Yearly data, 2013 to 2018, from all the states and union territories of India as per the World Health Organization-Global Observatory on Donation and Transplantation (WHO-GODT) format, were analyzed and tabulated. The various national and international legislation, advisories, and reports that mandated establishment of national regulatory bodies were studied. Comparisons were drawn, noting points of similarity and contrast between analogous organizations.
In the WHO Madrid Report 2004, the international advisory highlighted the need for a national transplantation agency for effective integrated development of donation and transplantation. Its parallel in India was the 2011 Amendment of the Transplantation of Human Organs Act 1994 to set NOTTO up with its first director in 2014, and also with a national donor and recipient registry to achieve transparent allocation. A challenging task for NOTTO was to collect from all transplant and/or retrieval centers their real-time data of donors, recipients, and transplants in the National Organ and Tissue Transplant Registry (NOTTR). However, NOTTO succeeded in collecting data offline from all 29 states and 7 union territories and submitted to GODT in 2019. There was a greater than 2-fold increase of deceased organ donors from 340 in 2013 (pre-NOTTO) to 875 in 2018 (post-NOTTO). The deceased organ donation rate went up from 0.27 to 0.65, and the total number of transplants went up from 4990 to 10,340 in the same period. All the outcome measures doubled or tripled, establishing the role of NOTTO. Albeit having differences, NOTTO is analogous to the National Transplant Organization of Spain and United Network of Organ Sharing of the United States.
The 2011 Amendment of THOA 1994 provided the basis for the establishment of NOTTO, which has been crucial in regulating organ donation and transplantation in India with the setting up of the NOTTR in 2015. NOTTO has been instrumental in augmenting all outcomes.
本研究旨在探讨印度国家器官与组织移植组织（NOTTO）的建立及其对器官捐赠和移植的影响。
对印度所有邦和联邦属地 2013 年至 2018 年按照世界卫生组织-全球器官捐献与移植观察站（WHO-GODT）格式提供的年度数据进行分析和制表。研究了要求建立国家监管机构的各种国家和国际立法、咨询意见和报告。对类似组织之间的相似和对比点进行了比较。
在 2004 年世卫组织马德里报告中，国际咨询意见强调需要建立一个国家移植机构，以有效整合捐赠和移植工作。印度的对应机构是 2011 年对《人体器官移植法》的修正案，该修正案于 2014 年设立了 NOTTO，并建立了国家供体和受体登记处，以实现透明分配。NOTTO 的一项艰巨任务是从所有移植和/或检索中心收集其国家器官和组织移植登记处（NOTTR）中供体、受体和移植的实时数据。然而，NOTTO 成功地从 29 个邦和 7 个联邦属地离线收集数据，并于 2019 年提交给 GODT。自 2011 年 NOTTO 成立以来，已故器官捐献者的数量从 2013 年的 340 人增加到 2018 年的 875 人，增加了两倍多。同期，已故器官捐献率从 0.27 上升到 0.65，移植总数从 4990 例上升到 10340 例。所有的结果指标都增加了一倍或两倍，确立了 NOTTO 的作用。尽管存在差异，但 NOTTO 与西班牙国家移植组织和美国器官共享联合网络类似。
1994 年《人体器官移植法》的修正案为 NOTTO 的成立提供了依据，该组织的成立对于规范印度的器官捐赠和移植至关重要，其于 2015 年建立了 NOTTR。NOTTO 在增加所有结果方面发挥了重要作用。
