Reddy Mettu S, Varghese Joy, Mathur Surender K
Department of Liver Transplantation & Hepatobiliary Surgery, Star Hospitals, Hyderabad, India.
Department of General & Transplant Hepatology, Gleneagles Health City, Chennai, India.
J Clin Exp Hepatol. 2025 Jan-Feb;15(1):102408. doi: 10.1016/j.jceh.2024.102408. Epub 2024 Sep 1.
India is the country with the third largest transplantation activity in the world but has one of the lowest deceased donation rates. The Transplantation of Human Organs Act was first enacted as law 29 years ago, its implementation has been non-uniform and growth in deceased donation has been slow and heterogenous. This review discusses the concept of brain death, ethics of deceased donation and organ allocation, Indian legislation in this area and the regulatory structure of the National Organ transplantation program. We also discuss current status of deceased donation and deceased donor liver transplantation in the country, identify variation in liver allocation policies across Indian states and identify areas of need and potential solutions.
印度是世界上器官移植活动第三多的国家,但却是尸体捐赠率最低的国家之一。《人体器官移植法》于29年前首次颁布成为法律,其实施并不统一,尸体捐赠的增长缓慢且不均衡。本综述讨论了脑死亡的概念、尸体捐赠和器官分配的伦理、印度在这一领域的立法以及国家器官移植计划的监管结构。我们还讨论了该国尸体捐赠和尸体供体肝移植的现状,确定了印度各邦肝分配政策的差异,并确定了需求领域和潜在解决方案。