腹腔镜手术与开腹手术治疗 BMI＞25kg/m2 的 II/III 期结肠癌患者的比较
Laparoscopic Open Surgery for Stage II/III Colon Cancer Patients With Body Mass Index >25 kg/m.
机构信息
Department of Surgery, Yokohama City University, Yokohama, Japan
Department of Surgery, Yokohama City University, Yokohama, Japan.
出版信息
In Vivo. 2020 Jul-Aug;34(4):2079-2085. doi: 10.21873/invivo.12011.
Abstract
AIM
To compare long- and short-term outcomes of laparoscopic surgery with those of open surgery for patients with colorectal cancer and body mass index over 25 kg/m Patients and Methods: This multicentre, retrospective study analysed clinical records and identified 178 patients with body mass index over 25 kg/m who underwent surgery for colon and rectosigmoid cancer between 2000 and 2016. After applying propensity score matching, 96 patients were finally included. The primary outcome was the 3-year recurrence-free survival rate, and the secondary outcomes were short-term results during and after surgery.
RESULTS
The 3-year recurrence-free survival rates were similar for the laparoscopic and open surgery groups. The laparoscopic surgery group had longer operative times but less blood loss and shorter periods of hospital stay. There were no differences in incidence of postoperative complications.
CONCLUSION
Laparoscopic and open surgeries had similar long-term outcomes for obese patients. Laparoscopic surgery is an effective option for this population.
摘要
目的
比较肥胖（体质量指数＞25kg/m2）结直肠癌患者接受腹腔镜手术与开腹手术的长期和短期疗效。
患者和方法
本多中心回顾性研究分析了临床记录，并纳入了 2000 年至 2016 年间接受结肠癌和直肠乙状结肠癌手术且体质量指数＞25kg/m2 的 178 例患者。应用倾向评分匹配后，最终纳入 96 例患者。主要结局为 3 年无复发生存率，次要结局为手术期间和术后的短期结果。
结果
腹腔镜手术组和开腹手术组的 3 年无复发生存率相似。腹腔镜手术组的手术时间较长，但术中出血量更少，住院时间更短。术后并发症发生率无差异。
结论
腹腔镜手术和开腹手术治疗肥胖患者的长期疗效相似。腹腔镜手术是该人群的有效选择。
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