Einiö Elina, Metsä-Simola Niina, Saarioja Saska, Martikainen Pekka, Korhonen Kaarina
Population Research Unit, Department of Social Research, Faculty of Social Sciences, University of Helsinki, Helsinki, Finland.
Laboratory of Population Health, Max Planck Institute for Demographic Research, Rostock, Germany.
Eur J Public Health. 2020 Oct 1;30(5):953-957. doi: 10.1093/eurpub/ckaa099.
Previous studies have shown that the risk of death is elevated after the death of a spouse. Limited evidence is available on changes in mental health before and after bereavement among individuals whose spouse dies of dementia.
We analyzed changes in the 3-month prevalence of antidepressant use for 5 years before and 3 years after widowhood for individuals whose spouses died of either dementia or other causes. The study used data of 41 855 widowed individuals and repeated-measures logistic regression analyses. Antidepressant use was based on the prescription register of Finland in 1995-2007.
Five years before widowhood, the 3-month prevalence for antidepressant use was 4% among widowing men and 6-7% among widowing women, regardless of whether the spouse died of dementia or other causes. Further changes in antidepressant use depended on a spouse's cause of death. Women whose spouses died of dementia experienced large increase in antidepressant use starting from 3 to 4 years prior to widowhood, whereas other widows did not experience large increase until after widowhood. The trajectories for men were similar. Antidepressant use following the death of a spouse with dementia stayed at a new heightened level after widowhood.
The trajectories of antidepressant use indicate that the process of losing a spouse to dementia is bad for mental health, already a few years prior to widowhood. There are no clear improvements in mental health after the death of a spouse with dementia. Support services for individuals whose spouses' dementia progresses are needed.
先前的研究表明,配偶去世后死亡风险会升高。关于配偶死于痴呆症的个体在丧偶前后心理健康变化的证据有限。
我们分析了配偶死于痴呆症或其他原因的个体在丧偶前5年和丧偶后3年中抗抑郁药使用的3个月患病率变化。该研究使用了41855名丧偶个体的数据,并进行了重复测量逻辑回归分析。抗抑郁药的使用基于1995 - 2007年芬兰的处方登记。
在丧偶前5年,无论配偶死于痴呆症还是其他原因,丧偶男性中抗抑郁药使用的3个月患病率为4%,丧偶女性中为6 - 7%。抗抑郁药使用的进一步变化取决于配偶的死因。配偶死于痴呆症的女性从丧偶前3至4年开始抗抑郁药使用大幅增加,而其他寡妇直到丧偶后才出现大幅增加。男性的情况类似。配偶死于痴呆症后,丧偶后抗抑郁药使用维持在一个新的较高水平。
抗抑郁药使用轨迹表明,在丧偶前几年,配偶因痴呆症去世的过程对心理健康有害。配偶死于痴呆症后,心理健康没有明显改善。需要为配偶痴呆病情进展的个体提供支持服务。