腹腔镜与开腹手术治疗低危型子宫内膜癌患者的生存结局比较。

Comparison of survival outcomes between laparoscopic and open surgery in patients with low-risk endometrial cancer.

机构信息

Department of Obstetrics and Gynecology, Faculty of Medicine, Kagoshima University, Kagoshima, Japan.

出版信息

Jpn J Clin Oncol. 2020 Oct 22;50(11):1261-1264. doi: 10.1093/jjco/hyaa116.

Abstract

OBJECTIVE

To evaluate the feasibility, safety and surgical outcomes of laparoscopic surgery for the treatment of low-risk endometrial cancer.

METHODS

Of 155 patients with low-risk endometrial cancer, who were included in this retrospective study between May 2008 and March 2017, 82 and 73 underwent laparoscopic and open surgery, respectively. Clinicopathological and surgical data, recurrence-free survival and overall survival were analyzed.

RESULTS

No statistically significant differences in median age, final pathological type, International Federation of Gynecology and Obstetrics stage and lymphovascular space involvement were observed between the laparoscopic and open surgery groups. No procedure in the laparoscopic surgery group was converted to open surgery. The median follow-up period was 60 months, with oncologic recurrence identified in three cases (one lung carcinoma and two pelvic cavity carcinomas) in the laparoscopic surgery group. There was no significant between-group difference in 5-year recurrence-free survival (laparoscopic surgery group: 96.3%, open surgery group: 92.6%) and overall survival (laparoscopic surgery group: 100%, open surgery group: 95.4%).

CONCLUSIONS

Laparoscopic surgery is a feasible and safe treatment for endometrial cancer and should be considered as a standard treatment option for low-risk endometrial cancer.

摘要

目的

评估腹腔镜手术治疗低危型子宫内膜癌的可行性、安全性和手术结局。

方法

本回顾性研究纳入了 2008 年 5 月至 2017 年 3 月期间的 155 例低危型子宫内膜癌患者,其中 82 例行腹腔镜手术,73 例行开腹手术。分析了临床病理和手术数据、无复发生存率和总生存率。

结果

腹腔镜手术组和开腹手术组的中位年龄、最终病理类型、国际妇产科联合会(FIGO)分期和脉管侵犯无统计学差异。腹腔镜手术组无手术中转开腹。中位随访时间为 60 个月,腹腔镜手术组有 3 例(1 例肺癌,2 例盆腔癌)发生肿瘤复发。两组 5 年无复发生存率(腹腔镜手术组:96.3%,开腹手术组:92.6%)和总生存率(腹腔镜手术组:100%,开腹手术组:95.4%)无统计学差异。

结论

腹腔镜手术是治疗子宫内膜癌的一种可行且安全的方法,应被视为低危型子宫内膜癌的标准治疗选择。

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