Akama Yuichi, Matsutani Takeshi, Hagiwara Nobutoshi, Umezawa Hiroki, Nomura Tsutomu, Hanawa Hidetsugu, Mishima Keisuke, Taniai Nobuhiko, Yoshida Hiroshi
Department of Gastrointestinal Hepato-Biliary-Pancreatic Surgery, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo, 113-8603, Japan.
Department of Digestive Surgery, Nippon Medical School Musashi Kosugi Hospital, 1-396 Kosugimachi, Nakahara-ku, Kawasaki-shi, Kanagawa, 211-8533, Japan.
Surg Case Rep. 2020 Jun 30;6(1):155. doi: 10.1186/s40792-020-00922-w.
Pyogenic spondylodiscitis is an extremely rare complication of esophagectomy for esophageal cancer.
A 70-year-old Japanese man, with a previous medical history of type 2 diabetes mellitus, coronary artery disease, and laryngeal cancer, received neoadjuvant chemotherapy and underwent thoracoscopic esophagectomy with gastric tube reconstruction for advanced esophageal cancer. Cervical esophagogastrostomy with circular-stapled end-to-side anastomosis was performed. However, partial necrosis in the gastric tube developed to form refractory anastomotic fistula. Two months after the initial surgery, debridement and free jejunal transfer reconstruction with the pectoralis major muscle flap were performed. Although the postoperative course of the second surgery was uneventful, the patient complained of severe lower back pain and fever. The patient was diagnosed with pyogenic spondylodiscitis according to the results of the magnetic resonance imaging. Enterobacter cloacae were isolated from the arterial blood culture. Sensitive antibiotics were administered continuously, and the patient required to use a lumbar corset for 2 months. Subsequently, his physiological signs and symptoms had completely disappeared.
To the best of our knowledge, this case study is the first study that reported pyogenic spondylodiscitis of the lumbar spine, a complication of cervical anastomotic fistula after surgery for advanced esophageal cancer.
化脓性脊椎间盘炎是食管癌食管切除术后极为罕见的并发症。
一名70岁的日本男性,既往有2型糖尿病、冠状动脉疾病和喉癌病史,接受了新辅助化疗,并因晚期食管癌接受了胸腔镜食管切除术及胃管重建术。采用圆形吻合器行颈段食管胃端侧吻合术。然而,胃管出现部分坏死,形成难治性吻合口瘘。初次手术后两个月,进行了清创术,并采用胸大肌皮瓣游离空肠移植重建术。尽管第二次手术的术后过程顺利,但患者仍主诉严重的下背部疼痛和发热。根据磁共振成像结果,患者被诊断为化脓性脊椎间盘炎。从动脉血培养中分离出阴沟肠杆菌。持续给予敏感抗生素治疗,患者需要佩戴腰托2个月。随后,他的生理体征和症状完全消失。
据我们所知,本病例研究是首例报道晚期食管癌手术后颈段吻合口瘘并发症导致腰椎化脓性脊椎间盘炎的研究。