疑似新型冠状病毒肺炎病例定义：确诊病例中最常见体征和症状的叙述性综述
Suspected COVID-19 case definition: a narrative review of the most frequent signs and symptoms among confirmed cases.
作者信息
Iser Betine Pinto Moehlecke, Sliva Isabella, Raymundo Vitória Timmen, Poleto Marcos Bottega, Schuelter-Trevisol Fabiana, Bobinski Franciane
机构信息
Universidade do Sul de Santa Catarina , Programa de Pós-Graduação em Ciências da Saúde , Tubarão , SC , Brasil.
Universidade do Sul de Santa Catarina , Faculdade de Medicina , Tubarão , SC , Brasil.
出版信息
Epidemiol Serv Saude. 2020 Jun 22;29(3):e2020233. doi: 10.5123/S1679-49742020000300018. eCollection 2020.
OBJECTIVE
to describe the most frequent signs and symptoms of infection by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).
METHODS
this is a narrative literature review carried out in April 2020; the search was performed on electronic databases and complemented with a manual review of the references of the selected papers and Brazilian Ministry of Health publications.
RESULTS
the spectrum of clinical disease was wide; fever, coughing and dyspnea were the most frequent signs/symptoms, however, they may not be present, thus hindering case definition; gastrointestinal symptoms and loss of taste or smell have been reported among mild cases; dyspnea was frequent among severe and fatal cases.
CONCLUSION
considering the scarcity of diagnostic tests and the diversity of symptoms, health services should use a sensitive case definition, in order to adopt appropriate surveillance, prevention and treatment actions.
目的
描述严重急性呼吸综合征冠状病毒2（SARS-CoV-2）感染最常见的体征和症状。
方法
这是一项于2020年4月进行的叙述性文献综述；检索在电子数据库中进行，并辅以对所选论文参考文献和巴西卫生部出版物的人工检索。
结果
临床疾病谱广泛；发热、咳嗽和呼吸困难是最常见的体征/症状，然而，它们可能不存在，从而阻碍病例定义；轻症病例中报告有胃肠道症状以及味觉或嗅觉丧失；呼吸困难在重症和致命病例中很常见。
结论
考虑到诊断检测的稀缺性和症状的多样性，卫生服务机构应采用敏感的病例定义，以便采取适当的监测、预防和治疗措施。
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