Laboratorio de Estudos do Movimento, Instituto de Ortopedia e Traumatologia (IOT), Hopital das Clinicas HCFMUSP, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, BR.
Programa de Ciencias do Envelhecimento, Universidade Sao Judas Tadeu (USJT), Sao Paulo, SP, BR.
Clinics (Sao Paulo). 2020 Jun 29;75:e1768. doi: 10.6061/clinics/2020/e1768. eCollection 2020.
Menopause marks the end of women's reproductive period and can lead to sarcopenia and osteoporosis (OP), increasing the risk of falls and fractures. The aim of this study is to evaluate the influence of normal and low bone mineral density (BMD) on muscular activity, observed through inflammatory edema when mapping using magnetic resonance imaging (MRI) on the quadriceps muscle of postmenopausal women.
This was a cross-sectional study involving 16 older women, who were divided into two groups: osteoporosis group (OG), older women with OP, and control group (CG), older women without OP. The groups were evaluated in terms of nuclear MRI exam before and after carrying out fatigue protocol exercises using an isokinetic dynamometer and squatting exercises.
The results of the present study showed that in intragroup comparisons, for both groups, there was a significant increase (p<0.05) in the T2 signal of the nuclear MRI in the quadriceps muscle after carrying out exercises using both thighs. In the intergroup comparison, no statistically significant difference was observed between the OG and CG, pre- (p=0.343) and postexercise (p=0.874).
The acute muscular activation of the quadriceps evaluated by T2 mapping on nuclear MRI equipment is equal in women with and without OP in the postmenopausal phase. BMD did not interfere with muscle response to exercise when muscle fatigue was reached.
绝经标志着女性生殖期的结束，可导致肌肉减少症和骨质疏松症（OP），增加跌倒和骨折的风险。本研究旨在评估正常和低骨密度（BMD）对股四头肌肌肉活动的影响，通过磁共振成像（MRI）对股四头肌进行炎症性水肿定位来观察。
这是一项横断面研究，涉及 16 名老年女性，分为骨质疏松症组（OG）和对照组（CG）。OG 为患有 OP 的老年女性，CG 为无 OP 的老年女性。两组均采用等速测力计和下蹲运动进行疲劳方案运动前后进行核 MRI 检查进行评估。
本研究结果表明，在组内比较中，两组股四头肌核 MRI 的 T2 信号在进行双腿运动后均显著增加（p<0.05）。在组间比较中，OG 和 CG 在运动前（p=0.343）和运动后（p=0.874）均无统计学差异。
在绝经后阶段，患有和不患有 OP 的女性股四头肌的 T2 图谱评估的急性肌肉激活是相等的。当肌肉疲劳达到时，BMD 不会干扰肌肉对运动的反应。
