Murakami Masahiro, Heng Hock Gan, Lim Chee Kin, Parnell Nolie K, Sola Mario
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, West Lafayette, Indiana, USA.
Department of Comparative Pathobiology, Purdue University, West Lafayette, Indiana, USA.
J Vet Intern Med. 2020 Sep;34(5):1867-1871. doi: 10.1111/jvim.15829. Epub 2020 Jul 1.
Ultrasonographic features of gastric wall edema have not been reported in dogs with hypoalbuminemia.
To describe the prevalence and ultrasonographic features of gastric wall thickening in dogs with hypoalbuminemia and analyze correlation with serum albumin concentrations.
Forty-two dogs with abdominal ultrasound and diagnosis of hypoalbuminemia (<2.3 g/dL).
Retrospective search in the medical records from 2018 to 2019 was performed. Ultrasound studies were reviewed and >5 mm were considered gastric wall thickening. The gastric wall changes such as thickness, layering appearance, echogenicity, echotexture, distribution of lesions, and presence of peritoneal effusion were recorded. Serial ultrasonographic examination and histopathological findings were recorded if available. Mean serum albumin concentration of dogs with and without gastric wall thickening was compared.
Prevalence of gastric wall thickening in dogs with hypoalbuminemia was 21.4% (95% confidence intervals 7.4-35.4%). Mean gastric wall thickness was 10.0 ± 2.0 mm. Preserved mucosal layer and thickening of submucosal layer were observed in all 9 dogs. Five dogs had 3-layer appearance in thickened submucosal layer. Diffuse wall thickening was observed in 6 dogs. All 9 dogs had peritoneal effusion. Subsequent changes of gastric wall thickening were observed in 3 dogs (range 4-70 days). Gastric wall edema was confirmed histopathologically in 2 dogs via necropsy. There was no correlation between serum albumin concentration of the dogs and gastric wall thickness.
Findings indicated that gastric wall edema is a common finding in dogs with hypoalbuminemia. However, serum albumin concentrations did not correlate with the gastric wall thickness.
低白蛋白血症犬胃壁水肿的超声特征尚未见报道。
描述低白蛋白血症犬胃壁增厚的发生率及超声特征，并分析其与血清白蛋白浓度的相关性。
42只接受腹部超声检查且诊断为低白蛋白血症（<2.3 g/dL）的犬。
对2018年至2019年的病历进行回顾性检索。复查超声检查结果，胃壁厚度>5 mm被视为胃壁增厚。记录胃壁的变化，如厚度、分层表现、回声性、回声纹理、病变分布及腹腔积液情况。如有连续超声检查及组织病理学检查结果也予以记录。比较有和无胃壁增厚犬的平均血清白蛋白浓度。
低白蛋白血症犬胃壁增厚的发生率为21.4%（95%置信区间7.4 - 35.4%）。平均胃壁厚度为10.0±2.0 mm。9只犬均观察到黏膜层保存及黏膜下层增厚。5只犬增厚的黏膜下层呈三层表现。6只犬观察到胃壁弥漫性增厚。9只犬均有腹腔积液。3只犬（4 - 70天）观察到胃壁增厚的后续变化。通过尸检在2只犬中组织病理学证实为胃壁水肿。犬的血清白蛋白浓度与胃壁厚度之间无相关性。
研究结果表明胃壁水肿在低白蛋白血症犬中是常见表现。然而，血清白蛋白浓度与胃壁厚度不相关。
