Freeman Caleb, Hull Christopher, Sontheimer Richard, Curtis Julia
University of Utah School of Medicine, Salt Lake City, UT, USA.
Dermatol Online J. 2020 Mar 15;26(3):13030/qt1rd1k82v.
Gel nails are a common artificial nail option. Ultraviolet (UV) nail lamps are commonly used to cure gel nails. Ultraviolet A radiation is a known mutagen that penetrates into the nail bed. Although previously reported, the role of UV nail lamps in the carcinogenesis of both keratinocyte carcinoma and melanoma remains controversial. Herein, we report a patient taking the photosensitizing agent hydrochlorothiazide who developed numerous squamous cell carcinomas on the dorsal hands and feet with a 10-year history of UV nail light exposure every 2-3 weeks.
凝胶指甲是一种常见的人工指甲选择。紫外线（UV）指甲灯常用于固化凝胶指甲。紫外线A辐射是一种已知的诱变剂，可穿透至甲床。尽管此前已有报道，但UV指甲灯在角质形成细胞癌和黑色素瘤致癌过程中的作用仍存在争议。在此，我们报告一名服用光敏剂氢氯噻嗪的患者，其在手背和足部出现了大量鳞状细胞癌，该患者有每2 - 3周使用UV指甲灯照射10年的病史。
