Fondelli M P, Cama A, Molinari A, Salomone G, Taccone A
Servizio di Radiologia, Istituto G. Gaslini, Genova Quarto.
Radiol Med. 1988 Jul-Aug;76(1-2):48-50.
The authors report their experience on 30 hemophilic children controlled at the Pediatric Institute G. Gaslini, Genoa, Italy; among the 30 patients, there were 4 cases of hemophilia A, and 1 of Von Willebrand disease. Various degrees of trauma in different sites had caused central neurological complications. In all cases CT, both in the immediate post-traumatic phase and later on, allowed both an early diagnosis and the follow-up of hemorrhagic lesions and late complications, even in absence of significant neurologic symptomatology; medical replacement treatment and neurosurgery, when needed, allowed a positive resolution of all cases. The authors believe this early-phase and follow-up diagnostic protocol, together with strict clinical and laboratory controls, to allow a prompt interdisciplinary therapeutic approach, which has preventive aims as well.
作者报告了他们对在意大利热那亚的G.加斯利尼儿科研究所接受治疗的30名血友病患儿的治疗经验；在这30名患者中，有4例甲型血友病，1例血管性血友病。不同部位的各种程度创伤均导致了中枢神经系统并发症。在所有病例中，无论是在创伤后即刻还是之后，CT都能够实现对出血性病变和晚期并发症的早期诊断及随访，即使在没有明显神经症状的情况下也是如此；必要时进行的药物替代治疗和神经外科手术使所有病例都得到了积极的治疗结果。作者认为，这种早期诊断及随访方案，连同严格的临床和实验室检查，能够实现迅速的多学科治疗方法，该方法也具有预防目的。
