Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Kansas City University of Medicine and Biosciences-Joplin, Joplin, MO, USA.
Br J Anaesth. 2020 Nov;125(5):835-842. doi: 10.1016/j.bja.2020.03.035. Epub 2020 Jun 28.
Reliable, high-quality research is essential to the field of anaesthesiology. Reproducibility and transparency have been investigated in the biomedical domain and in the social sciences, with both lacking to provide necessary information to reproduce the study findings. In this study, we investigated 14 indicators of reproducibility in anaesthesiology research.
We used the National Library of Medicine catalogue to search for all anaesthesiology journals that are MEDLINE indexed and provide English texts. PubMed was searched with the list of journals to identify all publications from January 1, 2014 to December 31, 2018. We randomly sampled 450 publications that fit the inclusion criteria for our analysis. Data extraction was then conducted in a blinded, duplicate fashion using a pilot-tested Google form.
The PubMed search of these journals identified 171 441 publications, with 28 310 being within the time frame. From the 450 publications sampled, 444 full-text publications were accessible. The majority of publications analysed did not have a statement regarding availability of data (164/188), analysis scripts (187/188), or study materials (160/188).
Anaesthesiology research needs to improve indicators of reproducibility and transparency. By making research publicly available and improving accessibility to detailed study components, primary research can be reproduced in subsequent studies and help contribute to the development of new practice guidelines.
可靠、高质量的研究对于麻醉学领域至关重要。可重复性和透明度已经在生物医学领域和社会科学领域进行了研究，但都缺乏提供必要信息以重现研究结果的能力。在这项研究中，我们调查了麻醉学研究中的 14 个可重复性指标。
我们使用美国国立医学图书馆目录搜索所有被 MEDLINE 索引并提供英文文本的麻醉学期刊。使用期刊列表在 PubMed 上搜索，以确定 2014 年 1 月 1 日至 2018 年 12 月 31 日期间的所有出版物。我们随机抽取了符合我们分析标准的 450 篇出版物。然后使用经过试验的 Google 表单以盲法、重复的方式进行数据提取。
对这些期刊的 PubMed 搜索确定了 171441 篇出版物，其中 28310 篇在时间范围内。从抽样的 450 篇出版物中，有 444 篇全文出版物可以获得。分析的大多数出版物都没有关于数据（164/188）、分析脚本（187/188）或研究材料（160/188）可用性的声明。
麻醉学研究需要提高可重复性和透明度指标。通过公开研究并提高对详细研究成分的可访问性，可以在后续研究中重现原始研究，并有助于制定新的实践指南。
