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Mining of epitopes on spike protein of SARS-CoV-2 from COVID-19 patients.

作者信息

Zhang Bao-Zhong, Hu Ye-Fan, Chen Lin-Lei, Yau Thomas, Tong Yi-Gang, Hu Jing-Chu, Cai Jian-Piao, Chan Kwok-Hung, Dou Ying, Deng Jian, Wang Xiao-Lei, Hung Ivan Fan-Ngai, To Kelvin Kai-Wang, Yuen Kwok Yung, Huang Jian-Dong

机构信息

CAS Key Laboratory of Quantitative Engineering Biology, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, 518055, China.

School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, University of Hong Kong, 3/F, Laboratory Block, 21 Sassoon Road, Hong Kong, China.

出版信息

Cell Res. 2020 Aug;30(8):702-704. doi: 10.1038/s41422-020-0366-x. Epub 2020 Jul 1.

DOI:10.1038/s41422-020-0366-x
PMID:32612199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7327194/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9198/7395085/1f65eb67022a/41422_2020_366_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9198/7395085/1f65eb67022a/41422_2020_366_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9198/7395085/1f65eb67022a/41422_2020_366_Fig1_HTML.jpg

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Science. 2020 May 15;368(6492). doi: 10.1126/science.aay5051.
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A noncompeting pair of human neutralizing antibodies block COVID-19 virus binding to its receptor ACE2.一对非竞争的人源中和抗体可阻断 COVID-19 病毒与其受体 ACE2 的结合。
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