Ferguson J L, DeSanto L W
Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN.
Laryngoscope. 1988 Sep;98(9):911-4. doi: 10.1288/00005537-198809000-00001.
Eighteen patients underwent pharyngoesophageal reconstruction with a free jejunal autotransplant in a one-stage procedure after circumferential resection for cancer of the pharynx and cervical esophagus. Of these, six had minor complications (fistulas) and six had major complications including abdominal bleeding, cervical bleeding, graft failure, and one surgical death. The mean survival was 427 days after resection and reconstruction (range, 120 to 866 days). Ten patients died of their disease, and four died of other causes. The site of failure was local in five and distant in five. In view of this high complication rate and unimpressive survival rate, the use of other lower-morbidity reconstructive options or staged procedures may need to be considered in poor surgical candidates.
18例患者在接受咽及颈段食管癌环形切除术后,一期采用游离空肠自体移植术进行咽食管重建。其中,6例出现轻微并发症(瘘),6例出现严重并发症,包括腹部出血、颈部出血、移植失败,还有1例手术死亡。切除与重建术后的平均生存期为427天(范围为120至866天)。10例患者死于疾病,4例死于其他原因。失败部位5例为局部,5例为远处。鉴于如此高的并发症发生率和不尽人意的生存率,对于手术条件较差的患者,可能需要考虑使用其他并发症发生率较低的重建方法或分期手术。