Department of Anesthesiology and Pain Medicine, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Curr Opin Anaesthesiol. 2020 Aug;33(4):589-593. doi: 10.1097/ACO.0000000000000883.
The number of elderly patients receiving non-operating room anaesthesia (NORA) has substantially increased because of clinical, epidemiological, social and economic reasons. Considering the high risk of anaesthesia-related adverse events in this population, along with the limitations of NORA, more specific knowledge and skills are required.
Advanced age appears to be an independent risk factor for anaesthesia-related adverse events in a NORA setting, similar to the traditional operating room. As significant changes occur in the pharmacological effects of anaesthetic agents with aging, reducing dosage and carefully titrating drugs are essential. Because NORA-related injury is frequently related to airway obstruction/respiratory depression, non-invasive respiratory activity monitoring is more useful for sedation of elderly patients. Additionally, advanced age increases the risk of aspiration and cognitive complications, even during sedation.
Elderly patients may greatly benefit from the lower invasiveness and faster recovery offered by interventional procedures. However, as they represent a highly heterogeneous population with large variations in physiological reserves and comorbidities, anaesthesiologists should strive to maintain the same practice standards throughout all anaesthetizing locations. Knowledge of the unique hazards associated with NORA in elderly patients may further enhance patient safety.Video abstract: NORA for elderly patients.mp4: http://links.lww.com/COAN/A66.
由于临床、流行病学、社会和经济等原因,接受非手术室麻醉(NORA)的老年患者数量大幅增加。考虑到该人群中与麻醉相关的不良事件风险较高,以及 NORA 的局限性,需要更具体的知识和技能。
与传统手术室一样,高龄似乎是 NORA 环境中与麻醉相关的不良事件的独立危险因素。随着麻醉药物的药效学随年龄的增长而发生显著变化,减少剂量和仔细滴定药物至关重要。由于与 NORA 相关的损伤通常与气道阻塞/呼吸抑制有关,因此非侵入性呼吸活动监测对于老年患者的镇静更为有用。此外,即使在镇静过程中,高龄也会增加误吸和认知并发症的风险。
老年患者可能会从介入性手术带来的较低侵入性和更快的恢复中获益匪浅。然而,由于他们是一个具有生理储备和合并症差异很大的高度异质人群,麻醉师应努力在所有麻醉场所保持相同的实践标准。了解与老年患者的 NORA 相关的独特危害可能会进一步提高患者安全性。
老年患者的 NORA.mp4:http://links.lww.com/COAN/A66。