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前路椎体拴系术治疗仍有生长潜力的青少年特发性脊柱侧凸:2至5年术后结果的回顾性研究

Anterior Vertebral Body Tethering for Adolescent Scoliosis with Growth Remaining: A Retrospective Review of 2 to 5-Year Postoperative Results.

作者信息

Hoernschemeyer Daniel G, Boeyer Melanie E, Robertson Madeline E, Loftis Christopher M, Worley John R, Tweedy Nicole M, Gupta Sumit U, Duren Dana L, Holzhauser Christina M, Ramachandran Venkataraman M

机构信息

University of Missouri Women's and Children's Hospital, Columbia, Missouri.

Departments of Orthopedic Surgery (D.G.H., M.E.B., C.M.L., J.R.W., N.M.T., S.U.G., D.L.D., and C.M.H.) and Pathology and Anatomical Sciences (M.E.B., D.L.D., and C.M.H.), University of Missouri, Columbia, Missouri.

出版信息

J Bone Joint Surg Am. 2020 Jul 1;102(13):1169-1176. doi: 10.2106/JBJS.19.00980.

Abstract

BACKGROUND

Anterior vertebral body tethering (VBT) is an early treatment option for progressive scoliosis in pediatric patients, allowing for continued deformity correction during normal growth. We report postoperative radiographic and clinical outcomes for patients treated with VBT.

METHODS

This clinical and radiographic retrospective review of 31 consecutive patients included an analysis of preoperative, perioperative, and postoperative details, including the Lenke classification; Cobb angle measurements of the proximal thoracic, main thoracic, and lumbar curves; the sagittal profile; and skeletal maturity. Successful outcomes were defined by a residual curve of ≤30° in skeletally mature patients who did not undergo a posterior spinal fusion (PSF).

RESULTS

Of the 31 patients treated, 29 met the inclusion criteria, and 2 were lost to follow-up. The mean patient age (and standard deviation) at the time of the surgical procedure was 12.7 ± 1.5 years (range, 10.2 to 16.7 years), with most patients classified as Risser grade 0 or 1 (52%) and Sanders stage 3 (32%). A mean of 7.2 ± 1.4 vertebral levels were instrumented, with a minimum preoperative Cobb angle of 42°. At the latest follow-up, 27 patients had reached skeletal maturity (Sanders stage ≥7) and 20 patients exhibited a curve magnitude ≤30°, for a success rate of 74%. A suspected broken tether occurred at ≥1 level in 14 patients (48%). Two patients underwent PSF and 4 had tether revision. The overall revision rate was 21% (6 of 29).

CONCLUSIONS

This study shows the success and revision rates as well as the impact of a suspected broken tether on the procedural success of VBT. Despite our patient population being slightly more mature at the time of the surgical procedure compared with previous studies, we had a higher success rate and a lower revision rate. A PSF was avoided in 93% of patients, indicating that VBT may be a reliable treatment option for adolescent scoliosis in skeletally immature individuals.

LEVEL OF EVIDENCE

Therapeutic Level IV. See Instructions for Authors for a complete description of levels of evidence.

摘要

背景

椎体前路栓系术(VBT)是小儿患者进展性脊柱侧弯的一种早期治疗选择,可在正常生长过程中持续矫正畸形。我们报告了接受VBT治疗患者的术后影像学和临床结果。

方法

对31例连续患者进行的这项临床和影像学回顾性研究,分析了术前、围手术期和术后的详细情况,包括Lenke分类;近端胸椎、主胸椎和腰椎曲线的Cobb角测量;矢状面形态;以及骨骼成熟度。成功的结果定义为未接受后路脊柱融合术(PSF)的骨骼成熟患者残余曲线≤30°。

结果

在接受治疗的31例患者中,29例符合纳入标准,2例失访。手术时患者的平均年龄(及标准差)为12.7±1.5岁(范围10.2至16.7岁),大多数患者Risser分级为0或1级(52%),Sanders分期为3期(32%)。平均固定7.2±1.4个椎体节段,术前最小Cobb角为42°。在最近一次随访时,27例患者达到骨骼成熟(Sanders分期≥7期),20例患者曲线幅度≤30°,成功率为74%。14例患者(48%)在≥1个节段发生疑似栓系断裂。2例患者接受了PSF,4例进行了栓系翻修。总体翻修率为21%(29例中的6例)。

结论

本研究显示了VBT的成功率、翻修率以及疑似栓系断裂对手术成功的影响。尽管与以往研究相比,我们的患者群体在手术时骨骼成熟度略高,但我们的成功率更高,翻修率更低。93%的患者避免了PSF,表明VBT可能是骨骼未成熟青少年脊柱侧弯可靠的治疗选择。

证据水平

治疗性IV级。有关证据水平的完整描述,请参阅作者指南。

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