Tartar T, Bakal U, Sarac M, Kazez A
Department of Pediatric Surgery, Firat University School of Medicine, Elazig, Turkey.
Niger J Clin Pract. 2020 Jul;23(7):1008-1012. doi: 10.4103/njcp.njcp_531_19.
The relationship hydatid cyst (HC) is a parasitic disease that is endemic worldwide.
To study the clinical findings and laboratory results of patients with hydatid disease.
Total number of patients (n = 78) who underwent surgery for HC disease from 2000 to 2017 were retrospectively evaluated. The patients' demographic characteristics, reasons for admission into hospital, lesion location and size, laboratory results, and complications were recorded.
Of the HCs, 59% and 26.9% were located in the liver and lungs, respectively. The rate of multiple organ involvement was 10.3%. A total of 16 (20.5%) cases had ruptured HCs (7 livers, 7 lungs, 1 spleen, and 1 omentum). There was no significant difference in the rate of eosinophilia between patients with and without cyst rupture (P = 0.9). Indirect hemagglutination (IHA) tests yielded negative results in 38.9% of the patients; among them, 32.1% had ruptured HCs. A negative IHA test result was significantly associated with rupture (P = 0.046). No significant difference between rupture and cyst size or location was found.
HC rupture was not correlated with cyst size. The sensitivity of serological tests and the blood eosinophil count was low, even in cases of ruptured HCs. The recurrence rate can be reduced by open surgery and medical treatments.
包虫囊肿（HC）是一种在全球流行的寄生虫病。
研究包虫病患者的临床症状和实验室检查结果。
回顾性评估了2000年至2017年间因HC疾病接受手术治疗的患者总数（n = 78）。记录了患者的人口统计学特征、入院原因、病变位置和大小、实验室检查结果以及并发症。
HC中，59%位于肝脏，26.9%位于肺部。多器官受累率为10.3%。共有16例（20.5%）患者的HC发生破裂（7例肝脏、7例肺部、1例脾脏和1例大网膜）。囊肿破裂患者与未破裂患者的嗜酸性粒细胞增多率无显著差异（P = 0.9）。间接血凝试验（IHA）在38.9%的患者中呈阴性结果；其中，32.1%的患者HC发生破裂。IHA试验阴性结果与破裂显著相关（P = 0.046）。未发现破裂与囊肿大小或位置之间存在显著差异。
HC破裂与囊肿大小无关。即使在HC破裂的病例中，血清学检测和血液嗜酸性粒细胞计数的敏感性也较低。开放手术和药物治疗可降低复发率。
