Kavitha M, Krishnaveni R, Swathi A M, M Abubacker M H
Department of Conservative Dentistry and Endodontics, Tamilnadu Government Dental College and Hospital, Dr. MGR Medical University, Tamil Nadu, India.
Niger J Clin Pract. 2020 Jul;23(7):1026-1029. doi: 10.4103/njcp.njcp_54_20.
When teeth have responded poorly to conventional endodontic treatment or when they cannot be treated adequately by nonsurgical means, surgical endodontics remains the treatment of choice. Healing of apical lesions occurs by repair, most of the time. "Repair is the healing of a wound by tissue that does not fully restore the architecture or function of the affected unit". Since this is not ideal, newer regenerative procedures that aim to restore lost tissue have been introduced. β -Tricalcium phosphate is an alloplastic bone graft material that forms a scaffold for closing the bony defect. It is osteoconductive. Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are platelet concentrates, rich in growth factors and they promote regeneration by osteoinduction. This article describes cases of bone augmentation with a combination of PRP + β -TCP and PRF + β -TCP for treatment of the chronic periapical lesion. The cases were followed for six months and one year and healing was evaluated quantitatively using cone beam computed tomography.
当牙齿对传统牙髓治疗反应不佳或无法通过非手术方法充分治疗时，外科牙髓治疗仍是首选治疗方法。大多数情况下，根尖病变通过修复愈合。“修复是指受损组织对伤口的愈合，但不能完全恢复受影响单位的结构或功能”。由于这并不理想，因此引入了旨在恢复丢失组织的新型再生程序。β-磷酸三钙是一种异质骨移植材料，可形成用于封闭骨缺损的支架。它具有骨传导性。富血小板血浆（PRP）和富血小板纤维蛋白（PRF）是富含生长因子的血小板浓缩物，它们通过骨诱导促进再生。本文描述了采用PRP+β-TCP和PRF+β-TCP联合进行骨增量治疗慢性根尖周病变的病例。对这些病例进行了6个月和1年的随访，并使用锥形束计算机断层扫描进行定量评估愈合情况。
