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采用再生方法管理根尖周病变的多学科方法:一例病例报告。

An interdisciplinary approach for the management of periapical lesion using regenerative approach: a case report.

作者信息

Jaiswal Priyanka, Kotecha Sakshi Vishal, Bhagat Shweta, Sedani Shweta, Thakare Akash

机构信息

Department of Periodontics and Implantology, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Sawangi, Meghe, Wardha, Maharashtra, India.

Department of Conservative Dentistry and Endodontics, Sharad Pawar Dental College, Datta Meghe Institute of Higher Education and Research, Sawangi, Meghe, Wardha, Maharashtra, India.

出版信息

J Med Case Rep. 2025 Jul 9;19(1):333. doi: 10.1186/s13256-025-05380-2.

DOI:10.1186/s13256-025-05380-2
PMID:40635079
Abstract

BACKGROUND

Periapical lesions are common sequelae of endodontic infections, often presenting as chronic apical periodontitis. These lesions result from the microbial invasion of the root canal system, leading to inflammation and subsequent bone resorption. While conventional root canal therapy is the primary treatment modality, it occasionally fails to resolve periapical pathology. In such cases, surgical intervention becomes necessary.

CASE PRESENTATION

This report presents the case of a 32-year-old female of Indian ethnicity with chief complaints of pain and pus discharge in the upper right front area in the past 2 months. Radiographic findings were evident, depicting periapical radiolucency. Upon debriding the lesion, it was observed to be creamish with irregular shape and size and, hence, it was sent for histopathological analysis. It was inferred to be a dental cyst associated with the right upper front region of the jaw.

CONCLUSION

This case report pinpoints the importance of considering the diagnosis of periapical lesions. It also adds to the point of treatment plan that can be followed as a multidisciplinary approach to challenging periapical lesions.

摘要

背景

根尖周病变是牙髓感染常见的后遗症,常表现为慢性根尖周炎。这些病变是由于微生物侵入根管系统,导致炎症及随后的骨质吸收。虽然传统的根管治疗是主要的治疗方式,但它偶尔无法解决根尖周病变。在这种情况下,手术干预就变得必要。

病例报告

本报告介绍了一名32岁的印度裔女性病例,其主要诉求是在过去2个月右上前方区域疼痛和有脓液排出。影像学检查结果明显,显示根尖周透射区。在对病变进行清创时,观察到病变呈乳白色,形状和大小不规则,因此将其送去进行组织病理学分析。推断其为与右上颌前部区域相关的牙囊肿。

结论

本病例报告指出了考虑根尖周病变诊断的重要性。它还补充了可作为处理具有挑战性的根尖周病变的多学科方法的治疗计划要点。

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本文引用的文献

1
Successful treatment of cystic lesion combining Cystectomy, Nonsurgical Endodontics and Vital Pulp Therapy of Mature Permanent Mandibular Molars: a Case Report with 19 Months Follow-Up.联合囊肿切除术、非手术牙髓治疗和成熟恒牙下颌磨牙活髓治疗成功治疗囊性病变:19个月随访病例报告
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Platelet-rich fibrin: Basics of biological actions and protocol modifications.富血小板纤维蛋白:生物学作用基础及方案改良
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Evaluation of healing by Cone Beam Computed Tomography (CBCT) using Platelet-Rich Plasma (PRP) + β -Tricalcium Phosphate (β -TCP) and Platelet Rich Fibrin (PRF) + β -Tricalcium Phosphate (β - TCP) in periapical lesions: Case report.
使用富血小板血浆(PRP)+β-磷酸三钙(β-TCP)和富血小板纤维蛋白(PRF)+β-磷酸三钙(β-TCP)通过锥形束计算机断层扫描(CBCT)评估根尖周病变愈合情况:病例报告
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Healing of Periapical Lesions After Surgical Endodontic Retreatment: A Systematic Review.牙髓外科再治疗后根尖周病变的愈合:一项系统评价
Cureus. 2020 Feb 7;12(2):e6916. doi: 10.7759/cureus.6916.
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Autologous platelet-rich derivatives along with alloplastic bone substitute in the management of complex perio-endo cases.自体富血小板衍生物联合异体骨替代物用于复杂牙周牙髓联合病变的治疗
J Indian Soc Periodontol. 2020 Mar-Apr;24(2):182-185. doi: 10.4103/jisp.jisp_81_19. Epub 2020 Mar 2.
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Recent advances in periodontal regeneration: A biomaterial perspective.牙周再生的最新进展:生物材料视角
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Synthesis of Hydroxyapatite, β-Tricalcium Phosphate and Biphasic Calcium Phosphate Particles to Act as Local Delivery Carriers of Curcumin: Loading, Release and In Vitro Studies.合成羟基磷灰石、β-磷酸三钙和双相磷酸钙颗粒作为姜黄素的局部递送载体:负载、释放及体外研究
Materials (Basel). 2018 Apr 12;11(4):595. doi: 10.3390/ma11040595.
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Bone grafts in dentistry.牙科中的骨移植
J Pharm Bioallied Sci. 2013 Jun;5(Suppl 1):S125-7. doi: 10.4103/0975-7406.113312.
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Tricalcium phosphate/hydroxyapatite (TCP-HA) bone scaffold as potential candidate for the formation of tissue engineered bone.磷酸三钙/羟基磷灰石(TCP-HA)骨支架作为组织工程骨形成的潜在候选材料。
Indian J Med Res. 2013 Jun;137(6):1093-101.
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Platelet-Rich Fibrin with β-Tricalcium Phosphate-A Noval Approach for Bone Augmentation in Chronic Periapical Lesion: A Case Report.富含血小板纤维蛋白与β-磷酸三钙——慢性根尖周病变骨增量的新方法:病例报告
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