希腊首例由于侵袭性分离株 ST-3129 引起的脑膜炎奈瑟菌对环丙沙星耐药的报告。
First report of meningococcal ciprofloxacin resistance in Greece due to invasive isolates of the sequence type ST-3129.
机构信息
National Meningitis Reference Laboratory, Department of Public Health Policy, School of Public Health, University of West Attica, 196 Alexandras Avenue, Athens, Greece.
Department of Epidemiological Surveillance and Intervention of the National Public Health Organization (NPHO), Athens, Greece.
出版信息
Eur J Clin Microbiol Infect Dis. 2020 Dec;39(12):2467-2470. doi: 10.1007/s10096-020-03965-x. Epub 2020 Jul 3.
A local outbreak caused by Neisseria meningitidis occurred in the migration camp in the Greek island of Lesbos during January-February 2020 (4 of 5 cases). In total, 5 samples positive for N. meningitidis were further investigated for sero-/genogroup, PorA, and WGS analysis. MenB was found among 3 cases, while in two cases, MenY was identified. WGS analysis and antibiotic susceptibility testing on the 2 culture positive MenB samples showed the new ST-3129, ciprofloxacin-resistant clone was circulating among the immigrants in the aforementioned camp. This is the first report of ciprofloxacin resistance in Greece.
2020 年 1 月至 2 月期间，希腊莱斯博斯岛移民营中爆发了由脑膜炎奈瑟菌引起的局部疫情（5 例病例中的 4 例）。共对 5 份脑膜炎奈瑟菌阳性样本进行了进一步的血清/基因群、PorA 和 WGS 分析。在 3 例中发现了 MenB，而在 2 例中鉴定出了 MenY。对 2 份培养阳性的 MenB 样本进行的 WGS 分析和抗生素药敏试验表明，上述营地的移民中存在新型 ST-3129、环丙沙星耐药克隆。这是希腊首例环丙沙星耐药的报告。
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