Division of Cardiology, Department of Internal Medicine, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Health Management Center, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
J Cardiovasc Electrophysiol. 2020 Sep;31(9):2499-2508. doi: 10.1111/jce.14649. Epub 2020 Jul 11.
Pulmonary vein isolation (PVI) is the cornerstone of atrial fibrillation (AF) ablation. However, this procedure remains complex and time-consuming, and the recurrence of AF after PVI is still unsatisfactory. Current technologies have improved our knowledge of the association between radiofrequency lesion creation and ablation parameters (power and duration), which triggered the development of high-power short-duration (HPSD). During the past decade, several preclinical and clinical studies have been conducted to confirm the feasibility, safety, and outcome of PVI ablation with HPSD or very high-power short-duration (vHPSD) settings, which increased electrophysiologists' interests in the utility of HPSD strategies. This paper describes the theoretical basis and recent research findings of HPSD or vHPSD ablation and summarizes the state-of-the-art evidence behind the role of this strategy in PVI.
肺静脉隔离（PVI）是房颤（AF）消融的基石。然而，该手术仍然复杂且耗时，PVI 后 AF 的复发情况仍不理想。目前的技术提高了我们对射频消融损伤与消融参数（功率和时间）之间关联的认识，这引发了高功率短时间（HPSD）的发展。在过去的十年中，已经进行了几项临床前和临床研究，以确认 HPSD 或超高功率短时间（vHPSD）设置下的 PVI 消融的可行性、安全性和结果，这增加了电生理学家对 HPSD 策略实用性的兴趣。本文描述了 HPSD 或 vHPSD 消融的理论基础和最新研究结果，并总结了该策略在 PVI 中作用的最新证据。
