Siegel D M, Baum J
Department of Pediatrics, University of Rochester School of Medicine and Dentistry, NY 14621.
J Rheumatol. 1988 Jun;15(6):976-7.
A number of conditions have been found to be associated with the HLA-B27 locus including ankylosing spondylitis, psoriatic spondylitis, Reiter's syndrome, juvenile arthritis, and others. An unusual clinical syndrome of "sausage-like" toe, or dactylitis, associated with an oligoarthritis involving the lower extremities has been reported in adults, as has HLA-B27 associated spondyloarthritis and enthesopathy in children. We describe 3 children with dactylitis of the toe who carry HLA-B27. Their course and treatment are presented, and the importance of establishing this diagnostic entity is discussed.
已发现许多病症与HLA - B27基因座相关，包括强直性脊柱炎、银屑病性脊柱炎、赖特综合征、青少年关节炎等。在成人中，曾报告过一种不寻常的临床综合征，即与累及下肢的少关节炎相关的“腊肠样”脚趾或指（趾）炎，儿童中也有HLA - B27相关的脊柱关节炎和附着点病的报告。我们描述了3例携带HLA - B27的脚趾指（趾）炎患儿。介绍了他们的病程和治疗情况，并讨论了确立这一诊断实体的重要性。
