Amsterdam UMC, University of Amsterdam, Dept. of Endocrinology and Metabolism, Amsterdam, the Netherlands.
Best Pract Res Clin Endocrinol Metab. 2020 Jul;34(4):101429. doi: 10.1016/j.beem.2020.101429. Epub 2020 Jun 17.
Thyroid dysfunction in pregnancy is strongly associated with adverse maternal and foetal outcomes. The effects of treatment are less clear. There is ongoing discussion on whom to treat, when to treat and whether treatment is beneficial. Although universal screening for thyroid disease during pregnancy increases diagnosis and treatment of thyroid dysfunction, there is currently insufficient evidence demonstrating a positive effect of screening on maternal and foetal outcomes. We therefore, at present, recommend against universal screening for thyroid disease before and during pregnancy.
妊娠期间甲状腺功能障碍与不良的母婴结局密切相关。治疗效果则不太明确。目前对于治疗人群、治疗时机以及治疗是否有益等问题仍存在争议。虽然对妊娠期间甲状腺疾病进行普遍筛查可以增加甲状腺功能障碍的诊断和治疗,但目前尚无充分证据表明筛查对母婴结局有积极影响。因此,目前我们不建议对妊娠前和妊娠期间的甲状腺疾病进行普遍筛查。