Thomaidis Thomas, Kallimanis George, May Gary, Zhou Pinghong, Sivanathan Visvakanth, Mosko Jeff, Triantafillidis John K, Teshima Christopher, Moehler Markus
2 Gastroenterology Clinic, Hygeia Hospital, Athens, Greece (Thomas Thomaidis, George Kallimanis).
Johannes Gutenberg University, Mainz, Germany (Thomas Thomaidis, Visvakanth Sivanathan, Markus Moehler).
Ann Gastroenterol. 2020 Jul-Aug;33(4):338-347. doi: 10.20524/aog.2020.0497. Epub 2020 May 25.
Biliary obstruction is common in pancreatobiliary malignancies and has a negative impact on the patient's quality of life, postoperative complications, and survival rates. Particularly in the last decade, there has been enormous progress regarding the diagnostic and therapeutic options in patients with malignant biliary obstruction. Endoscopy has given a new insight in this direction and novel techniques have been developed for the better characterization and treatment of malignant strictures. We herein summarize the available data on the different endoscopic techniques, and clarify their role in the diagnosis and treatment of malignant biliary obstructive disease. Finally, we propose an algorithm that can facilitate management decisions in these patients.
胆管梗阻在胰胆恶性肿瘤中很常见,对患者的生活质量、术后并发症及生存率均有负面影响。特别是在过去十年间,恶性胆管梗阻患者的诊断和治疗选择取得了巨大进展。内镜检查在这方面带来了新的认识,并且已经开发出新技术用于更好地识别和治疗恶性狭窄。我们在此总结了不同内镜技术的现有数据,并阐明它们在恶性胆管梗阻性疾病诊断和治疗中的作用。最后,我们提出一种算法,可有助于这些患者的管理决策。