Tominaga S
Okinaka Memorial Institute for Medical Research, Tokyo, Japan.
FEBS Lett. 1988 Oct 10;238(2):315-9. doi: 10.1016/0014-5793(88)80503-9.
The amount of murine mRNA for the beta-subunit of integrin is enriched 6-fold when BALB/c-3T3 cells traverse from the G0 state to the G1 phase, whereas it remains at the basal level when the cells are growing continuously. The peak of its appearance is at 10 h after serum stimulation. The increase in integrin mRNA at a specific point in cell proliferation may be correlated with growth-signal transduction.
当BALB/c - 3T3细胞从G0期进入G1期时，整合素β亚基的鼠源mRNA量增加了6倍，而当细胞持续生长时，其保持在基础水平。其出现的峰值在血清刺激后10小时。细胞增殖特定阶段整合素mRNA的增加可能与生长信号转导相关。
