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本文引用的文献

1
Scientific Opinion on the update of the list of QPS-recommended biological agents intentionally added to food or feed as notified to EFSA.关于向欧洲食品安全局通报的有意添加到食品或饲料中的QPS推荐生物制剂清单更新的科学意见。
EFSA J. 2017 Mar 14;15(3):e04664. doi: 10.2903/j.efsa.2017.4664. eCollection 2017 Mar.

DSM 32291作为所有动物物种青贮饲料添加剂的安全性和有效性。

Safety and efficacy of DSM 32291 as a silage additive for all animal species.

作者信息

Rychen Guido, Aquilina Gabriele, Azimonti Giovanna, Bampidis Vasileios, Bastos Maria de Lourdes, Bories Georges, Chesson Andrew, Cocconcelli Pier Sandro, Flachowsky Gerhard, Gropp Jürgen, Kolar Boris, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Mantovani Alberto, Ramos Fernando, Villa Roberto Edoardo, Wallace Robert John, Wester Pieter, Brozzi Rosella, Saarela Maria

出版信息

EFSA J. 2018 Mar 20;16(3):e05202. doi: 10.2903/j.efsa.2018.5202. eCollection 2018 Mar.

DOI:10.2903/j.efsa.2018.5202
PMID:32625836
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7009375/
Abstract

Following a request from the European Commission, the Panel on Additives and Products or Substances used in Animal Feed was asked to deliver a scientific opinion on the safety and efficacy of a strain of when used as a technological additive intended to improve ensiling at a proposed application rate of 5 × 10 CFU kg/fresh matter. The species .  is considered by EFSA to be suitable for the qualified presumption of safety approach to safety assessment and not to require specific demonstration of safety other than the absence of resistance to antibiotics of human and veterinary significance. As the identity of the strain was clearly established and as no antibiotic resistance was detected, the use of the strain in the production of silage is presumed safe for livestock species, consumers of products from animals fed treated silage and the environment. In the absence of data, no conclusion can be drawn on the skin and eye irritancy of the additive. The additive should be considered a potential respiratory sensitiser. DSM 32291 at a minimum dose of 5 × 10 CFU/kg has the potential to improve the production of silage from easy and moderately difficult to ensile materials by decreasing dry matter loss and protein degradation during ensiling.

摘要

应欧盟委员会的要求,动物饲料添加剂及产品或物质专家小组被要求就一种菌株用作技术添加剂时的安全性和有效性发表科学意见,该添加剂拟以5×10⁶CFU/千克新鲜物质的建议施用量用于改善青贮。该菌株……被欧洲食品安全局认为适用于安全性评估的合格假定安全性方法,除了不存在对人和兽医具有重要意义的抗生素耐药性外,无需进行特定的安全性证明。由于该菌株的身份已明确确定且未检测到抗生素耐药性,因此该菌株用于青贮生产对家畜物种、食用经处理青贮饲料的动物产品的消费者以及环境被假定为安全的。在缺乏数据的情况下,无法就该添加剂的皮肤和眼睛刺激性得出结论。该添加剂应被视为潜在的呼吸道致敏剂。DSM 32291在最低剂量5×10⁶CFU/千克时,有可能通过减少青贮过程中的干物质损失和蛋白质降解,提高从易于青贮和中等难度青贮的原料生产青贮饲料的产量。