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苯甲酸作为断奶仔猪和育肥猪的技术饲料添加剂的安全性和有效性。

Safety and efficacy of benzoic acid as a technological feed additive for weaned piglets and pigs for fattening.

作者信息

Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Dusemund Birgit, Kouba Maryline, Kos Durjava Mojca, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Sanz Yolanda, Villa Roberto Edoardo, Woutersen Ruud, Aquilina Gabriele, Bories Georges, Chesson Andrew, Nebbia Carlo, Renshaw Derek, Innocenti Matteo Lorenzo, Gropp Jürgen

出版信息

EFSA J. 2019 Jan 16;17(1):e05527. doi: 10.2903/j.efsa.2019.5527. eCollection 2019 Jan.

DOI:10.2903/j.efsa.2019.5527
PMID:32626073
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7009120/
Abstract

The additive under assessment is pure benzoic acid (> 99.8%), manufactured in the form of flakes. It is intended to be used as a technological feed additive (acidity regulator) in feedingstuffs for weaned piglets and pigs for fattening, with maximum contents of 5,000 and 10,000 mg/kg complete feed, respectively. Benzoic acid is safe for weaned piglets at 5,000 mg/kg complete feed, and at 10,000 mg/kg complete feed for pigs for fattening. The use of benzoic acid in feedingstuffs for piglets and pigs for fattening at the maximum application rate will not affect exposure of consumers to residues or metabolites of concern via food from treated animals. Therefore, the use of benzoic acid as technological additive in feeds for pigs to a maximum inclusion level of 10,000 mg/kg is considered safe for consumers. Benzoic acid is a skin and eye irritant but is not considered to be a skin sensitiser. Exposure via inhalation is unlikely. The use of benzoic acid in feedingstuffs for piglets and pigs for fattening will not pose a risk for the environment. Benzoic acid is efficacious as an acidity regulator in feedingstuffs for weaned piglets and pigs for fattening.

摘要

所评估的添加剂为纯苯甲酸(>99.8%),呈片状生产。它拟用作断奶仔猪和育肥猪饲料中的技术饲料添加剂(酸度调节剂),在全价饲料中的最大含量分别为5000毫克/千克和10000毫克/千克。苯甲酸在全价饲料中含量为5000毫克/千克时对断奶仔猪安全,在全价饲料中含量为10000毫克/千克时对育肥猪安全。以最大使用量在仔猪和育肥猪饲料中使用苯甲酸,不会影响消费者通过食用经处理动物的肉类而接触到相关残留物或代谢物。因此,在猪饲料中以最高添加水平10000毫克/千克使用苯甲酸作为技术添加剂,对消费者而言被认为是安全的。苯甲酸是一种皮肤和眼睛刺激物,但不被认为是皮肤致敏剂。通过吸入接触的可能性不大。在仔猪和育肥猪饲料中使用苯甲酸不会对环境构成风险。苯甲酸作为断奶仔猪和育肥猪饲料中的酸度调节剂是有效的。

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本文引用的文献

1
Assessment of the application for renewal of authorisation of VevoVitall (benzoic acid) as feed additive for weaned piglets and pigs for fattening.对VevoVitall(苯甲酸)作为断奶仔猪和育肥猪饲料添加剂的授权续期申请的评估。
EFSA J. 2017 Dec 13;15(12):e05093. doi: 10.2903/j.efsa.2017.5093. eCollection 2017 Dec.
2
Safety and efficacy of VevoVitall (benzoic acid) as feed additive for minor porcine species.VevoVitall(苯甲酸)作为小型猪饲料添加剂的安全性和有效性。
EFSA J. 2017 Oct 17;15(10):e05026. doi: 10.2903/j.efsa.2017.5026. eCollection 2017 Oct.