Zhai Hengxiao, Ji Chihai, Walsh Maria Carol, Bergstrom Jon, Potot Sebastien, Wang Heng
DSM (China) Animal Nutrition Research Center, Bazhou 065799, China.
Key Laboratory of Comprehensive Prevention and Control for Severe Clinical Animal Diseases, South China Agricultural University, Guangzhou 510642, China.
Animals (Basel). 2021 Apr 14;11(4):1124. doi: 10.3390/ani11041124.
African swine fever virus is one of the most highly contagious and lethal viruses for the global swine industry. Strengthening biosecurity is the only effective measure for preventing the spread of this viral disease. The virus can be transmitted through contaminated feedstuffs and, therefore, research has been conducted to explore corresponding mitigating measures. The purpose of the current study was to test a combination of pure benzoic acid and a blend of nature identical flavorings for their ability to reduce African swine fever viral survival in feed. This virus was inoculated to feed with or without the supplementation of the test compounds, and the viral presence and load were measured by a hemadsorption test and quantitative real time polymerase chain reaction. The main finding was that the combination of pure benzoic acid and nature identical flavorings could expedite the reduction in both viral load and survival in a swine feed. Therefore, this solution could be adopted as a preventive measure for mitigating the risk of contaminated feed by African swine fever virus.
非洲猪瘟病毒是全球养猪业中传染性最强、致死性最高的病毒之一。加强生物安全措施是预防这种病毒性疾病传播的唯一有效措施。该病毒可通过受污染的饲料传播，因此，人们开展了相关研究以探索相应的缓解措施。本研究的目的是测试纯苯甲酸和天然等同香料混合物降低饲料中非洲猪瘟病毒存活率的能力。将该病毒接种到添加或不添加测试化合物的饲料中，并通过血细胞吸附试验和定量实时聚合酶链反应测量病毒的存在和载量。主要发现是，纯苯甲酸和天然等同香料的组合可以加快猪饲料中病毒载量的降低和病毒存活时间的缩短。因此，该解决方案可作为一项预防措施，以降低饲料被非洲猪瘟病毒污染的风险。
