Yoon Hyungjoon, Lee Hyunjoo, Kim Seungchul, Joo Jongkil
Pusan National University Graduate School, Busan, Republic of Korea.
Pusan National University Hospital Medical Research Institute, Busan, Republic of Korea.
Ginekol Pol. 2020;91(6):313-319. doi: 10.5603/GP.2020.0060.
The aim of this study is to evaluate the impact of ovarian endometrioma according to its size on the serum anti-Mullerian hormone (AMH) levels compared to that of other benign ovarian cysts.
The current study retrospectively evaluated preoperative serum AMH level and its association to presenting ovarian cyst size which were measured in clinical setting. Women with surgically diagnosed endometrioma or other benign ovarian cysts were included. All patients underwent transvaginal or transrectal ultrasonography to determine the size of the ovarian cysts. Preoperative serum AMH level was checked and evaluated according to histologic type of the cyst, which were endometrioma or other benign ovarian cysts, respectively. Both groups were classified into ≤ 4 cm, > 4 cm and ≤ 8 cm, > 8 cm and ≤ 12 cm, > 12 cm according to the diameter of cyst and analyzed the difference of mean AMH levels in both groups.
There was no significant difference in preoperative serum AMH level between the two groups (3.36 ± 2.3 versus 3.76 ± 2.64, p = 0.331). The difference of preoperative AMH levels according to categorized cyst size also was not statistically significant in both groups.
Preoperative serum AMH levels were not statistically different between endometrioma and other benign ovarian cyst groups and were not related to the size of endometrioma.
本研究旨在评估与其他良性卵巢囊肿相比，不同大小的卵巢子宫内膜异位囊肿对血清抗苗勒管激素（AMH）水平的影响。
本研究回顾性评估了临床测量的术前血清AMH水平及其与卵巢囊肿大小的关系。纳入经手术诊断为子宫内膜异位囊肿或其他良性卵巢囊肿的女性。所有患者均接受经阴道或经直肠超声检查以确定卵巢囊肿的大小。根据囊肿的组织学类型（分别为子宫内膜异位囊肿或其他良性卵巢囊肿）检查并评估术前血清AMH水平。根据囊肿直径将两组分为≤4 cm、>4 cm且≤8 cm、>8 cm且≤12 cm、>12 cm，并分析两组平均AMH水平的差异。
两组术前血清AMH水平无显著差异（3.36±2.3对3.76±2.64，p = 0.331）。两组中根据囊肿大小分类的术前AMH水平差异也无统计学意义。
子宫内膜异位囊肿组和其他良性卵巢囊肿组术前血清AMH水平无统计学差异，且与子宫内膜异位囊肿大小无关。
