剩余牙槽嵴吸收的局部病理生理机制：前列腺素作为骨吸收的介质

A local pathophysiologic mechanism of the resorption of residual ridges: prostaglandin as a mediator of bone resorption.

作者信息

Nishimura I, Szabo G, Flynn E, Atwood D A

机构信息

Harvard School of Dental Medicine, Boston, Mass.

出版信息

J Prosthet Dent. 1988 Sep;60(3):381-8. doi: 10.1016/0022-3913(88)90290-9.

DOI:10.1016/0022-3913(88)90290-9

PMID:3262741

Abstract

The role of PG as a bone resorption mediator in RRR was investigated in the rat model and the following may be concluded from the data. 1. PG is suggested to be a mediator of the RRR. 2. The continuous and localized bone resorption in RRR may be caused by continuous synthesis of local PG. 3. PG producing cells and specific stimuli responsible for RRR are still unknown.

摘要

在大鼠模型中研究了前列腺素（PG）作为类风湿性关节炎（RRR）中骨吸收介质的作用，从数据中可得出以下结论。1. 提示PG是RRR的一种介质。2. RRR中持续且局部的骨吸收可能是由局部PG的持续合成引起的。3. 产生PG的细胞以及RRR的特定刺激因素仍然未知。