前列腺素作为大鼠实验性牙齿移动诱导骨吸收的介质。
Prostaglandin as a mediator of bone resorption induced by experimental tooth movement in rats.
作者信息
Yamasaki K, Miura F, Suda T
出版信息
J Dent Res. 1980 Oct;59(10):1635-42. doi: 10.1177/00220345800590101301.
PMID:6932420
Abstract
Administration of indomethacin inhibited the appearance of osteoclasts and bone resorption induced by experimental tooth movement in rats. Effects were limited to groups injected within 12 h after treatment. Prostaglandin E1 or E2 solutions injected in gingiva lying near the upper first molar caused the appearance of osteoclasts and bone resorption.
摘要
吲哚美辛的给药抑制了大鼠实验性牙齿移动诱导的破骨细胞出现和骨吸收。作用仅限于治疗后12小时内注射的组。在上颌第一磨牙附近牙龈注射前列腺素E1或E2溶液会导致破骨细胞出现和骨吸收。
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