Department of Chemistry, University of Dschang, Dschang, Cameroon.
Institute of Organic Chemistry, Johannes Gutemberg-University of Mainz, Mainz, Germany.
Nat Prod Res. 2022 Jan;36(2):515-522. doi: 10.1080/14786419.2020.1789632. Epub 2020 Jul 6.
A new ceramide is being reported herein together with six known compounds from the methanol extract of the leaves of (Hochst. ex A.Rich.) Engl. The metabolites were obtained through repeated open column chromatography and were characterized by spectroscopic and spectrometric techniques. The radical-scavenging activity of the crude extract and isolated compounds was evaluated using the DPPH radical. The obtained results suggest the studied species as prominent candidate to fight reactive oxygen species (ROS).
本文报道了从 (Hochst. ex A.Rich.)Engl. 的叶甲醇提取物中分离得到的一种新神经酰胺和六种已知化合物。代谢产物通过反复的开管柱色谱法获得,并通过光谱和光谱技术进行了表征。利用 DPPH 自由基评价了粗提取物和分离化合物的自由基清除活性。研究结果表明,所研究的物种是对抗活性氧物种(ROS)的候选物质。