Department of Obstetrics and Gynecology, Prenatal and Preimplantation Genetic Diagnosis, Fetal Therapy, Microcitemico Pediatric Hospital "Antonio Cao", Cagliari, Sardinia, Italy.
J Perinat Med. 2020 Nov 26;48(9):943-949. doi: 10.1515/jpm-2020-0208.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a new coronavirus, was first identified in December 2019 in Wuhan, China and spread rapidly, affecting many other countries. The disease is now referred to as coronavirus disease 2019 (COVID-19).The Italian government declared a state of emergency on 31st January 2020 and on 11th March World Health Organization (WHO) officially declared the COVID-19 outbreak a global pandemic. Although the COVID-19 incidence remained considerably lower in Sardinia than in the North Italy regions, which were the most affected, the field of prenatal screening and diagnosis was modified because of the emerging pandemic. Data on COVID-19 during pregnancy are so far limited. Since the beginning of the emergency, our Ob/Gyn Department at Microcitemico Hospital, Cagliari offered to pregnant patients all procedures considered essential by the Italian Ministry of Health. To evaluate the influence of the COVID-19 pandemic on the activities of our center, we compared the number of procedures performed from 10th March to 18th May 2020 with those of 2019. Despite the continuous local birth rate decline, during the 10-week pandemic period, we registered a 20% increment of 1st trimester combined screening and a slight rise of the number of invasive prenatal procedures with a further increase in chorionic villi sampling compared to amniocentesis. Noninvasive prenatal testing remained unvariated. The request for multifetal pregnancy reduction as a part of the growing tendency of voluntary termination of pregnancy in Sardinia increased. The COVID-19 pandemic provides many scientific opportunities for clinical research and study of psychological and ethical issues in pregnant women.
严重急性呼吸综合征冠状病毒 2（SARS-CoV-2）是一种新型冠状病毒，于 2019 年 12 月在中国武汉首次被发现，并迅速传播，影响了许多其他国家。这种疾病现在被称为 2019 年冠状病毒病（COVID-19）。意大利政府于 2020 年 1 月 31 日宣布进入紧急状态，世界卫生组织（WHO）于 3 月 11 日正式宣布 COVID-19 疫情为全球大流行。尽管 COVID-19 在撒丁岛的发病率明显低于受影响最严重的意大利北部地区，但由于这一新兴的大流行，产前筛查和诊断领域发生了变化。目前关于 COVID-19 孕妇的数据有限。自紧急情况开始以来，我们卡利亚里的 Microcitemico 医院的妇产科部门向孕妇提供了意大利卫生部认为必不可少的所有程序。为了评估 COVID-19 大流行对我们中心活动的影响，我们比较了 2020 年 3 月 10 日至 5 月 18 日期间与 2019 年同期进行的程序数量。尽管当地出生率持续下降，但在 10 周的大流行期间，我们发现 1 期联合筛查增加了 20%，侵袭性产前程序的数量略有上升，绒毛膜绒毛取样较羊膜穿刺术进一步增加。非侵入性产前检测保持不变。多胎妊娠减少的请求作为撒丁岛自愿终止妊娠趋势增加的一部分而增加。COVID-19 大流行为临床研究和研究孕妇的心理和伦理问题提供了许多科学机会。
