Torizumi K, Aibata H, Kiji S, Ueyoshi A, Kiura Y, Okamoto Y, Tuda T, Ota K
Department of Radiology, Wakayama Medical College, Japan.
Radioisotopes. 1988 Jul;37(7):398-401. doi: 10.3769/radioisotopes.37.7_398.
The accumulation rate and velocity of 99mTc-hydroxymethylene diphosphonate (99mTc-HMDP) in hip joints were determined within four minutes after a bolus of injection of 99mTc-HMDP in the patients with hip joint disorders. There exist a significant relationship between accumulation velocity of 99mTc-HMDP in the affected joint and serum osteocalcin in the patients with eight cases of degenerative osteoarthropathy and six cases of femoral necrosis. This result indicates that the accumulation velocity of 99mTc-HMDP in the affected joint is likely to become a marker of bone turnover in hip joint disorder.
在髋关节疾病患者静脉注射大剂量99m锝-亚甲基二膦酸盐(99mTc-HMDP)后的4分钟内,测定其在髋关节中的积聚率和速度。在8例退行性骨关节炎和6例股骨头坏死患者中,患侧关节99mTc-HMDP的积聚速度与血清骨钙素之间存在显著相关性。这一结果表明,患侧关节99mTc-HMDP的积聚速度可能成为髋关节疾病中骨转换的一个标志物。