Zhao Yu, Yin Kun, Zhao Huiling, Peng Zeli
The First Affiliated Hospital of Dali University of Orthopedic trauma, Yunnan Province, China.
Medicine (Baltimore). 2020 Jul 2;99(27):e20970. doi: 10.1097/MD.0000000000020970.
There has been a paucity of cohort trials directly comparing multiple cannulated screws (MCS) and sliding hip screws (SHS) in femoral neck fractures at any level. Thus, a well-conducted clinical trial with an adequate sample size is urgently needed. We undertake a retrospective study to compare outcomes in patients who undertake MCS or SHS fixation for femoral neck fractures.
A retrospective review of femoral neck fractures performed with SHS or MCS between February 2016 and June 2018 was conducted with Institutional Review Board approval in the First Affiliated Hospital of Dali University of Orthopedic Trauma. All cases were performed by a single surgeon. Of these, we included 180 patients (90 hips) that were performed surgery in treatment of femoral neck fractures. All patients received the same standardized postoperative multimodal pain protocol and the same postoperative rehabilitation program. The primary endpoint was Harris Hip Score. Secondary outcome measures include operation time, length of hospital stay, incision length, patient satisfaction, and postoperative complications. Multivariate linear and regression analyses was used to identify independent predictors of outcome. A P-value of <.05 was defined as statistical significance.
We hypothesize that both treatments provide comparable outcomes.
This study protocol was registered in Research Registry (researchregistry5638).
在任何层面上，直接比较多枚空心螺钉（MCS）和动力髋螺钉（SHS）治疗股骨颈骨折的队列试验都很少。因此，迫切需要开展一项样本量充足的高质量临床试验。我们进行了一项回顾性研究，以比较接受MCS或SHS固定治疗股骨颈骨折患者的治疗结果。
在大理大学第一附属医院创伤骨科，经机构审查委员会批准，对2016年2月至2018年6月期间采用SHS或MCS治疗的股骨颈骨折进行回顾性研究。所有病例均由同一外科医生实施。其中，我们纳入了180例接受股骨颈骨折手术治疗的患者（90髋）。所有患者均接受相同的标准化术后多模式疼痛方案和相同的术后康复计划。主要终点是Harris髋关节评分。次要结局指标包括手术时间、住院时间、切口长度、患者满意度和术后并发症。采用多变量线性和回归分析来确定结局的独立预测因素。P值<.05被定义为具有统计学意义。
我们假设两种治疗方法的疗效相当。
本研究方案已在研究注册库（researchregistry5638）注册。
