Bosch Floris T M, Nisio Marcello Di, Büller Harry R, van Es Nick
Department of Internal Medicine, Tergooi Hospitals, 1213 XZ Hilversum, The Netherlands.
Department of Vascular Medicine, Amsterdam Cardiovascular Science, Amsterdam UMC, University of Amsterdam, 1105 AZ Amsterdam, The Netherlands.
J Clin Med. 2020 Jul 1;9(7):2069. doi: 10.3390/jcm9072069.
Upper extremity deep vein thrombosis (UEDVT) accounts for 5% of all deep vein thromboses (DVTs). UEDVT may be complicated by post thrombotic syndrome and pulmonary embolism, and early recognition and prompt start of anticoagulant treatment are key. Primary UEDVT, also known as Paget-von Schrötter syndrome, is associated with repeated or sudden physical activity of the upper arm and venous outflow obstruction due to anatomical variations. Secondary UEDVT is often associated with malignancy or use of intravenous devices, such as central venous catheters or pacemaker leads. Although the diagnosis and treatment of UEDVT have many similarities with DVT of the lower extremities, knowledge of specific aspects regarding UEDVT is important to guide optimal management. In this review, we will discuss the epidemiology, diagnosis, and treatment of UEDVT based on the current literature.
上肢深静脉血栓形成（UEDVT）占所有深静脉血栓形成（DVT）的5%。UEDVT可能并发血栓形成后综合征和肺栓塞，早期识别并及时开始抗凝治疗是关键。原发性UEDVT，也称为佩吉特-施罗特综合征，与上臂反复或突然的体力活动以及由于解剖变异导致的静脉流出道梗阻有关。继发性UEDVT通常与恶性肿瘤或静脉内装置的使用有关，如中心静脉导管或起搏器导线。尽管UEDVT的诊断和治疗与下肢DVT有许多相似之处，但了解UEDVT的具体方面对于指导最佳管理很重要。在本综述中，我们将根据当前文献讨论UEDVT的流行病学、诊断和治疗。
