INRAE, UR RiverLy, Laboratoire d'écotoxicologie, F-69625 Villeurbanne, France.
ENTPE, INRAE, CNRS UMR 5023 LEHNA, rue Maurice Audin, 69518 Vaulx-en-Velin CEDEX, France.
Int J Mol Sci. 2020 Jul 1;21(13):4704. doi: 10.3390/ijms21134704.
We explore the delayed consequences of parental exposure to environmentally relevant cadmium concentrations on the life-history traits throughout generations of the freshwater crustacean . We report the preliminary results obtained during a challenging one-year laboratory experiment in this environmental species and propose the use of population modeling to interpret the changes in offspring life-history traits regarding their potential demographic impacts. The main outcome of this first long-term transgenerational assay is that the exposure of spawners during a single gametogenesis cycle (3 weeks) could result in severe cascading effects on the life-history traits along three unexposed offspring generations (one year). Indeed, we observed a decrease in F1 reproductive success, an early onset of F2 offspring puberty with reduced investment in egg yolk reserves, and finally a decrease in the growth rate of F3 juveniles. However, the analysis of these major transgenerational effects by means of a Lefkovitch matrix population model revealed only weak demographic impacts. Population compensatory processes mitigating the demographic consequences of parental exposure seem to drive the modification of life-history traits in offspring generations. This exploratory study sheds light on the role of population mechanisms involved in the demographic regulation of the delayed effects of environmental toxicity in wild populations.
我们探讨了父母在一生中暴露于环境相关浓度的镉对淡水甲壳类动物后代生活史特征的延迟影响。我们报告了在这个环境物种的为期一年的挑战性实验室实验中获得的初步结果，并提出使用种群模型来解释后代生活史特征的变化，以了解其对潜在人口统计学的影响。这项首次长期跨代测定的主要结果是，在单一配子发生周期（3 周）期间暴露于亲代会导致未暴露的三代后代（一年）的生活史特征发生严重的级联效应。实际上，我们观察到 F1 生殖成功率下降，F2 后代青春期提前，卵黄储备投资减少，最后 F3 幼体生长速度下降。然而，通过 Lefkovitch 矩阵种群模型对这些主要的跨代效应进行分析，仅发现了微弱的人口统计学影响。减轻亲代暴露后人口统计学后果的人口补偿过程似乎驱动了后代生活史特征的改变。这项探索性研究揭示了种群机制在野生种群中环境毒性延迟效应的人口统计学调节中的作用。
