大麻是阿片类药物使用障碍的诱导性药物。
Cannabis as a Gateway Drug for Opioid Use Disorder.
机构信息
Arthur Robin Williams, M.D., M.B.E., is an Assistant Professor, Division on Substance Use Disorders, Columbia University Department of Psychiatry and a Research Scientist, New York State Psychiatric Institute.
出版信息
J Law Med Ethics. 2020 Jun;48(2):268-274. doi: 10.1177/1073110520935338.
Abstract
Cannabis use in some individuals can meaningfully introduce risk for the initiation of opioid use and development of opioid use disorder. These risks may be particularly high during adolescence when cannabis use may disrupt critical periods of neurodevelopment. Current research studying the combination of genetic and environmental factors involved in substance use disorders is poorly understood. More research is needed, particularly to identify which adolescents are most at risk and to develop effective interventions addressing contributing factors such as trauma and psychiatric comorbidity.
摘要
一些个体使用大麻可能会显著增加阿片类药物使用的风险，导致阿片类药物使用障碍。这些风险在青少年时期可能特别高，因为大麻使用可能会干扰神经发育的关键时期。目前对研究物质使用障碍相关的遗传和环境因素组合的研究知之甚少。需要更多的研究，特别是要确定哪些青少年风险最大，并制定有效的干预措施来解决创伤和精神共病等促成因素。
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