Department of Orthopaedic Surgery, Shengjing Hospital of China Medical University, Sanhao Road 36, Shenyang City, 110001, Liaoning Province, People's Republic of China.
Shandong Weigao Orthopaedic Device co., Ltd., Weihai, 264300, People's Republic of China.
J Orthop Surg Res. 2020 Jul 6;15(1):244. doi: 10.1186/s13018-020-01764-w.
To design a new type of screw for minimally invasive atlantoaxial anterior transarticular screw (AATS) fixation with a diameter that is significantly thicker than that of traditional screws, threaded structures at both ends, and a porous metal structure in the middle. The use of a porous metal structure can effectively promote bone fusion and compensate for the disadvantages of traditional AATSs in terms of insufficient fixation strength and difficulty of bone fusion. The biomechanical stability of this screw was verified through finite element analysis. This instrument may provide a new surgical option for the treatment of atlantoaxial disorders.
According to the surgical procedure, the new type of AATS was placed in a three-dimensional atlantoaxial model to determine the setting of relevant parameters such as the diameter, length, and thread to porous metal ratio of the structure. According to the results of measurement, the feasibility and safety of the new AATS were verified, and a representative finite element model of the upper cervical vertebrae was chosen to establish, and the validity of the model was verified. Then, finite element-based biomechanical analysis was performed using three models, i.e., atlantoaxial posterior pedicle screw fixation, traditional atlantoaxial AATS fixation, and atlantoaxial AATS fixation with the new type of screw, and the biomechanical effectiveness of the novel AATS was verified.
By measuring the atlantoaxial parameters, the atlantoaxial CT data of the representative 30-year-old normal adult male were selected to create a personalized 3D printing AATS screw. In this case, the design parameters of the new screw were determined as follows: diameter, 6 mm; length of the head thread structure, 10 mm; length of the middle porous metal structure, 8 mm (a middle porous structure containing an annular cylinder ); length of the tail thread structure, 8 mm; and total length, 26 mm. Applying the same load conditions to the atlantoaxial complex along different directions in the established finite element models of the three types of atlantoaxial fusion modes, the immediate stability of the new AATS is similar with Atlantoaxial posterior pedicle screw fixation.They are both superior to traditional atlantoaxial anterior screw fixation.The maximum local stress on the screw head in the atlantoaxial anterior surgery was less than those of traditional atlantoaxial anterior surgery.
By measuring relevant atlantoaxial data, we found that screws with a larger diameter can be used in AATS surgery, and the new AATS can make full use of the atlantoaxial lateral mass space and increase the stability of fixation. The finite element analysis and verification revealed that the biomechanical stability of the new AATS was superior to the AATS used in traditional atlantoaxial AATS fixation. The porous metal structure of the new AATS may promote fusion between atlantoaxial joints and allow more effective bone fusion in the minimally invasive anterior approach surgery.
设计一种新型经皮寰枢椎前路经关节螺钉(AATS)固定用螺钉,其直径明显大于传统螺钉,两端带有螺纹结构,中间为多孔金属结构。使用多孔金属结构可以有效促进骨融合,并弥补传统 AATS 固定强度不足和骨融合困难的缺点。通过有限元分析验证了该螺钉的生物力学稳定性。该器械可能为寰枢椎疾病的治疗提供一种新的手术选择。
根据手术步骤,将新型 AATS 放置在三维寰枢椎模型中,以确定结构的直径、长度和螺纹与多孔金属的比例等相关参数的设置。根据测量结果,验证新型 AATS 的可行性和安全性,并选择具有代表性的上颈椎有限元模型进行建立,并验证模型的有效性。然后,使用三种模型(寰枢椎后路椎弓根螺钉固定、传统寰枢椎 AATS 固定和新型 AATS 固定)进行基于有限元的生物力学分析,验证新型 AATS 的生物力学效果。
通过测量寰枢椎参数,选择具有代表性的 30 岁正常成年男性的寰枢椎 CT 数据,创建个性化 3D 打印 AATS 螺钉。在这种情况下,新型螺钉的设计参数确定如下:直径 6mm;头部螺纹结构长度 10mm;中间多孔金属结构长度 8mm(包含环形圆柱的中间多孔结构);尾部螺纹结构长度 8mm;总长度 26mm。在建立的三种寰枢椎融合模式的有限元模型中,沿不同方向对寰枢椎复合体施加相同的载荷条件,新型 AATS 的即刻稳定性与寰枢椎后路椎弓根螺钉固定相似,均优于传统的寰枢椎前路螺钉固定。在传统的寰枢椎前路手术中,螺钉头部的最大局部应力小于传统的寰枢椎前路手术。
通过测量相关寰枢椎数据,我们发现较大直径的螺钉可用于 AATS 手术,新型 AATS 可充分利用寰枢椎侧块空间,增加固定稳定性。有限元分析和验证表明,新型 AATS 的生物力学稳定性优于传统的寰枢椎前路 AATS 固定。新型 AATS 的多孔金属结构可能促进寰枢关节融合,并允许在前路微创手术中更有效地进行骨融合。