伽马经颅交流电刺激治疗精神分裂症阴性症状患者的病例系列研究。
Gamma transcranial alternating current stimulation in patients with negative symptoms in schizophrenia: A case series.
机构信息
Department. of Psychiatry and Psychotherapy, Klinikum der Universität München, Munich, Germany.
Department. of Psychiatry and Psychotherapy, Klinikum der Universität München, Munich, Germany; Klinik für Psychiatrie, Psychotherapie und Psychosomatik der Universität Augsburg, Bezirkskrankenhaus Augsburg, Medizinische Fakultät, Universität Augsburg, Augsburg, Germany.
出版信息
Neurophysiol Clin. 2020 Sep;50(4):301-304. doi: 10.1016/j.neucli.2020.06.004. Epub 2020 Jul 4.
Non-invasive transcranial brain stimulation therapies, such as transcranial direct current stimulation, have been found to improve negative symptoms in schizophrenia. Another new technique is transcranial alternating current stimulation (tACS). Here we report a series of three patient treated with twice-daily 10min prefrontal 40Hz tACS stimulation over ten days. Patients showed an improvement in the Positive and Negative Syndrome Scale, Scale for the Assessment of Negative Symptoms, and subjective well-being. Furthermore, there was an improvement in the Trail Making Test and word fluency. ytACS merits further investigation in the treatment of schizophrenia symptoms.
非侵入性经颅脑刺激疗法，如经颅直流电刺激，已被发现可改善精神分裂症的阴性症状。另一种新技术是经颅交流电刺激（tACS）。在这里，我们报告了三例患者接受为期十天、每天两次、每次 10 分钟的前额叶 40Hz tACS 刺激治疗的情况。患者的阳性和阴性症状量表、阴性症状评定量表和主观幸福感均有改善。此外，连线测试和词语流畅性也有所改善。tACS 在治疗精神分裂症症状方面值得进一步研究。
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