U.O.Fisica Sanitaria, Azienda Ospedaliero-Universitaria Pisana, Via Roma n.67, 56125, Pisa, Italy.
Dipartimento di Fisica E.Fermi, Università di Pisa, L.go B.Pontecorvo n.3, 56127, Pisa, Italy.
Eur Radiol Exp. 2020 Jul 7;4(1):38. doi: 10.1186/s41747-020-00165-2.
To propose a practical and simple method to individually evaluate the average absorbed dose for digital breast tomosynthesis.
The method is based on the estimate of incident air kerma (k) on the breast surface. An analytical model was developed to calculate the k from the tube voltage, tube load, breast thickness, x-ray tube yield, and anode-filter combination. A homogeneous phantom was employed to simulate the breast in experimental measurements and to assess the dose-depth relationship. The k values were employed to calculate the "average absorbed breast dose" (2ABD) index. Four mammographic units were used to develop and test our method under many conditions close to clinical settings. The average glandular dose (AGD) calculated following the method described by Dance et al., and the 2ABD computed through our method (i.e., from the exposure parameters) were compared in a number of conditions.
A good agreement was obtained between the k computed through our model and that measured under different clinical conditions: discrepancies < 6% were found in all conditions. 2ABD matches with a good accuracy the AGD for a 100% glandular-breast: the minimum, maximum, and mean differences were < 0.1%, 7%, and 2.4%, respectively; the discrepancies increase with decreasing breast glandularity.
The proposed model, based on only few exposure parameters, represents a simple way to individually calculate an index, 2ABD, which can be interpreted as the average absorbed dose in a homogeneous phantom, approximating a 100% glandular breast. The method could be easily implemented in any mammographic device performing DBT.
提出一种实用且简单的方法,用于单独评估数字乳腺断层摄影的平均吸收剂量。
该方法基于对乳房表面入射空气比释动能(k)的估计。开发了一种分析模型,用于从管电压、管电流、乳房厚度、X 射线管产额和阳极滤过组合计算 k。使用均匀体模进行实验测量,以模拟乳房并评估剂量-深度关系。使用 k 值计算“平均乳腺吸收剂量”(2ABD)指数。使用四个乳腺摄影单元在许多接近临床设置的条件下开发和测试我们的方法。根据 Dance 等人描述的方法计算的平均腺体剂量(AGD)和通过我们的方法(即通过曝光参数)计算的 2ABD 在许多条件下进行了比较。
通过我们的模型计算出的 k 值与在不同临床条件下测量的值之间存在良好的一致性:在所有条件下发现差异<6%。2ABD 与 100%腺体乳腺的 AGD 具有很好的准确性:最小、最大和平均差异分别<0.1%、7%和 2.4%;差异随着乳腺腺体密度的降低而增加。
该模型基于少数几个曝光参数,代表了一种简单的方法,可以单独计算一个指数 2ABD,该指数可以解释为均匀体模中平均吸收剂量,近似于 100%腺体乳腺。该方法可以很容易地在执行 DBT 的任何乳腺摄影设备中实施。